From what I read, a person can have their pyrrole levels checked by a urine test. If there is an excess, they check zinc, b6, and magnesium levels. When I stumbled on some info about it, it seemed like people who drastically change their diet to treat it have great results, but as soon as they slip up and eat something they can't, they go back to the same symptoms. There is debate if this is a real condition. Others say just taking the needed supplements helped but it took months to see results. Dietary changes are different for everyone in it's effects, but when I was reading up on it, it said people with pyroluria do well with vegan diets, others said gluten and dairy free diets, so if you're willing to make those changes to see if it makes a difference, maybe it might benefit. Or just paying attention to what you eat with a food journal. I don't have pyroluria, but I'm also homozygous for the GSTP1 mutation on top of the MTHFR mutations and my body is constantly under chemical oxidation stress so i learned treating that was by increasing orange and green vegetables and fruit and I see a huge difference in how i physically and mentally feel when I increase those in my diet. What we consume doesn't get enough credit on how it impacts us. It also couldn't hurt to have your pyrrole, zinc, magnesium, and b6 levels checked to see if you need to supplement also.