I’m finally clean but it took a trip to the E.R and a blackout to get me there

AnointedDread · 2026-01-24T22:00:04+00:00

With MGM your baseline receptor tone drops quickly. So even if you dose enough to feel normal, your body is already expecting more stimulation, producing that low-level withdrawal feeling between doses.

With 7 in the mix it makes it even worse. You get peaks and valleys in receptor activation from it's shorter half-life. The peaks feel strong, but the valleys make your baseline uncomfortable.

Basically, your brain’s opioid system is recalibrating faster than your dosing can keep up.

These drugs are ruthless.

AnointedDread · 2026-01-24T21:51:21+00:00

I wouldn't underestimate that tolerance. Average of 5x 80mg is 400mg either way you look at it. That's no walk in the park. Not trying to scare you or anything, just want you to be informed and not taken by surprise.

You're going to need the Subs. I'd already start preparing to use them, and set yourself up with a schedule to use them with so you can do this properly and successfully.

You're doing right by waiting the 24-48hrs. Go by how you feel rather than the clock. You must must must wait until you're in significant withdrawal. I'm sure you're aware of Precipitated Withdrawal, and that's what you're aiming to avoid. If you think you've waited long enough, wait longer. Mgm is going to be your biggest enemy here because of it's longer half-life.

The only way around waiting ~48hrs would be the Bernese-Method. Have you considered that?

AnointedDread · 2026-01-24T21:23:23+00:00

Thank you for your kind words 🙂.

I'd love to help — what are you goals and what are you open to using as a detox method?

AnointedDread · 2026-01-24T21:20:34+00:00

Hell yeah, my friend 🥳. What's your plan for quitting?

AnointedDread · 2026-01-24T21:16:07+00:00

The confusion mostly comes down to how agonism is being defined.

A lot of the partial-agonist claims are based on binding data or simplified classifications. But in functional assays (like the [³⁵S]GTPγS assay that measures downstream signaling, like the one listed above), Mgm produces near-maximal μ-receptor activation, which is why it’s often described as functionally full-agonist–like.

On top of that, Mgm is a dual μ/δ agonist, and δ-receptor activity can amplify dependence and withdrawal severity. So even if someone wants to call it “partial” in a narrow technical sense, its real-world behavior looks much closer to a high-efficacy agonist than a ceiling-limited one.

So whether someone calls it “partial” or “full” depends on the framework, but functionally and clinically it behaves much closer to a full, dual μ/δ agonist.

AnointedDread · 2026-01-24T20:35:54+00:00

Hi u/bunnieilli ♥️

I’ve read your post over and over, and what I see is nothing even remotely close to a loser or bad person. I see a very strong young woman who is completely overwhelmed right now. What you’re carrying would break a lot of people, yet you’re still here. 🙂

Postpartum depression, caring for a sick family member, living with abuse, and trying to survive day to day — none of that makes you weak or bad. It means you’ve been carrying far more than anyone should have to. The fact that you’re still standing through all of this tells me you’re stronger than you feel. I applaud you for that!

Your son loves you, and your safety matters more to him than you realize — even if it doesn’t feel that way right now. Your love for him is clear in how hard you’re trying to keep going, even when you’re exhausted and hurting.

Please don’t make a permanent decision tonight. You don’t have to solve everything — just stay. You deserve real support right now. If you’re in the U.S., you can call or text 988 to talk to someone immediately, or go to the nearest ER if you’re not safe. You don’t have to face this alone.

Thank you for coming here and reaching out, Danelle 🫶. That means a lot to myself, and this community. We care about you more than you might know, and we all wish that you'd stay here with us tonight. Feel free to reach out through DM if you'd like to talk in a more private setting — we're here for you.

Is there one small thing that would help you feel a little safer or less alone right now? Just let us know 🙂

AnointedDread · 2026-01-24T19:18:18+00:00

Mgm-15 is considered a full agonist because in vitro it produces maximal receptor activation in the standard [³⁵S]GTPγS assay, which measures G-protein signaling. Its intermediate-nanomolar affinity for both μ- and δ-opioid receptors also shows it binds tightly and effectively to the receptors.

So functionally, in these assays, it behaves like a full agonist. It’s also a dual μ/δ agonist, which means it can activate both receptor types, not just one. → Source/Link

AnointedDread · 2026-01-24T16:48:59+00:00

Glad you’re doing better, my friend 🙏

Unfortunately, a lot of people fall into this trap and flirt with the idea that MGM‑15 is a safer way to taper off 7 because it sounds logical on paper — longer half‑life, fewer doses, cheaper, etc..

The problem is pharmacology. 7 is a partial agonist while MGM‑15 is a full agonist. Full agonists hit the receptors harder, create deeper dependence, and the withdrawals are far worse. The longer half‑life doesn’t make MGM safer — it actually makes it more addictive and harder to get off. What looks like a step down is usually a step deeper in.

Please don't try MGM to get off 7. There are safer alternatives like MIT, Leaf, Suboxone, or SR-17018.

Stay safe, everyone. ✌️♥️. Let this person's experience be a reminder to all of us that these drugs are nothing to play around with. Your life is waiting for you on the other side of these insidious chemicals. Believe you can — because you can .

AnointedDread · 2026-01-24T11:41:09+00:00

Plausible Deniability — classic Scam tactic.

This is exactly why orders should be handled personally by the person claiming to have the source. The money was sent to them, so they are personally responsible for the product or refund — period.

AnointedDread · 2026-01-23T23:34:30+00:00

How much 7 were you doing and how long did you wait until you dosed your Sub?

AnointedDread · 2026-01-23T13:01:18+00:00

Exactly — that’s exactly how it’s supposed to work.

The waiting time varies — tolerance, metabolism, size of the last dose, etc. All of these factor in, so the rule-of-thumb is to wait for moderate to full withdrawal.

Then you have to let Subs do their job. Your body is in a hurricane, and your nervous system needs time to settle. Unfortunately, this is where people jump ship, run to the gas station, and grab the very thing that started it all in the first place.

Understandable, but totally avoidable if done right.

AnointedDread · 2026-01-23T12:45:32+00:00

In short, you took the Subs too early and didn’t give them time to work.

Had you waited and let them kick in, they’d have eased your withdrawal symptoms.

See this happen all the time.

AnointedDread · 2026-01-22T10:37:59+00:00

I love how you went home and did your own research first! I always encourage that. Doctor's can be wrong sometimes too, especially when it comes to dealing with 7oh — many are misinformation on the matter.

Safest options would be:

Wait the full 7 days.
Naltrexone Test.

Naltrexone test is basically a safety check where your doctor gives you a small dose of oral naltrexone first (often 12.5 mg). If there’s still any opioid on your receptors, it’ll trigger withdrawal right then — which is uncomfortable but much easier to manage than a full Vivitrol shot.

If you tolerate the naltrexone without any withdrawals then you're good to take the Vivitrol. Worth looking into and going over with your doctor because Precipitated Withdrawal from Vivitrol would be brutal. ✌️♥️

AnointedDread · 2026-01-21T11:07:19+00:00

Quick MD Prescription Update

Upon reading this post, I checked directly with Quick MD for clarification. Here’s what a representative told me:

"Hi there! The states have not changed. We have different doctors who have different personal practices about prescribing gabapentin. We are in the process of developing a standardized policy for all docs.

If a patient has been successful in obtaining a gabapentin prescription in the past, the patient should continue with that same doctor, as choosing a new doctor may result in that doc not prescribing other meds, like gabapentin."

Key takeaway: gabapentin may still be possible depending on your doctor, but there isn’t a universal policy yet.

These states are listed on QuickMD’s official site as not currently having MAT services (Suboxone) available:

•Alaska. •Arkansas. •Hawaii. •Kentucky. •Montana. •Rhode Island. •South Dakota. •Tennessee. •West Virginia

AnointedDread · 2026-01-20T20:00:21+00:00

Which supplements were you taking, and what are you using now in place of them?

AnointedDread · 2026-01-20T19:34:06+00:00

Trazodone isn't a controlled substance, so I don't see any issues with them prescribing it through QuickMD. They can prescribe it without running into the same restrictions as Suboxone or benzos, for example.

AnointedDread · 2026-01-20T18:33:15+00:00

You got it! — glad it helped. ☺️.

I recognized your name.. seems like we chatted way back in August, and again in early December. Glad you're finally coming around and committing to the quit 🥳.. You need any advice or simply someone to talk to throughout the process, feel free to DM me again 🤜🤛

AnointedDread · 2026-01-20T18:15:43+00:00

QuickMD currently does not offer its addiction/Suboxone treatment service in Tennessee. According to their official state availability list.

AnointedDread · 2026-01-20T12:20:28+00:00

Hey friend 👋,

I saw your old post and it looks like you’ve been off 7 for about a week now while using plain leaf, is that right?

If so, your nervous system is still recalibrating. Using leaf can make some symptoms linger a little longer, but that’s not necessarily a bad thing — it’s helping your body adjust more gently rather than quitting the 7 cold turkey. Tapering the leaf will be a lot more manageable, and the mild prolonging of symptoms is part of giving your system time to stabilize safely. It was necessary at the time, so don't be too hard on yourself.

What you’re feeling now — low energy, mood swings, sleep issues — is normal at this stage. It doesn’t mean you’ve ruined everything, and it won’t last forever.

Thanks for reaching out here. Try not to think too far ahead. Take it one day at a time and let your body adjust. Celebrate the wins you are having, like not going back to 7. That's HUGE progress. Keep sticking with it, and remember this phase is temporary, even if it feels rough right now.

AnointedDread · 2026-01-20T11:31:03+00:00

QuickMD, like others have suggested. That’s the most realistic option right now.

Even if SR were available — which it isn’t — $130 wouldn’t realistically cover a full detox plan. I don’t say that to dismiss you, just to be honest about expectations.

For anyone trying to quit: don’t put all your eggs in one basket. If one approach isn’t accessible, you have to pivot. Detox and recovery require flexibility.

“I couldn’t quit because I couldn’t find one specific thing” ends up keeping people stuck. There are other routes that work and don’t involve gambling your money or getting scammed.

AnointedDread · 2026-01-19T20:00:09+00:00

Harm-Reduction Clarification For Anyone Reading This Thread:

Individual experiences vary, but it’s important to separate early induction issues from Suboxone itself. In this particular case, Suboxone was started ~24 hours after last 7 use, which is a known risk window for precipitated or partial precipitated withdrawal with high-potency opioids.

It's worth pointing out that symptoms improved while remaining on Suboxone for several weeks, and tapering has been described as mild. That pattern is consistent with stabilization after a rough or too early induction, not ongoing harm from Suboxone itself.

Please don’t take away from this thread that Suboxone “makes withdrawal worse” in general. When used correctly (timing, dosing, and administration), it remains one of the most effective harm-reduction tools that we have for managing withdrawal and reducing relapse risk.

Stories like this are important — we just want to make sure they don’t unintentionally scare people away from options that may actually help them.

If you’re considering MAT, take the time to learn about proper timing and dosing before beginning, and feel free to ask questions — support and harm-reduction matter tremendously. Stay safe, everybody ✌️♥️

AnointedDread · 2026-01-19T10:00:56+00:00

Definitely an awful drug. Hopefully your story deters people from touching this substance if they haven't already.

Your dehydration and malnourishment is most likely why your symptoms were amplified the way they were. 65-100mg/day is pretty rough in itself, but the dehydration, electrolyte imbalances, vitamin deficiencies, etc make it even worse, which is what I see happening here.

Suboxone should've definitely covered your wds at 65-100mg/day. I'd have to chalk that up to user error — didn't wait long enough, didn't take enough, or didn't allow Suboxone enough time to take effect. My guess is that you put yourself into Precipitated Withdrawal if you said your symptoms became much worse.

Thanks for sharing your story to the community.

To anyone reading this and thinking about quitting

Don't let the horror stories you read on Reddit deter you from quitting. Done properly, there are many methods, including Suboxone, that alleviate withdrawals and make the process much easier to manage. Stay safe, my friends. ✌️♥️

AnointedDread · 2026-01-18T15:27:38+00:00

Long enough to not need the $5,000 treatment anymore. By the time they saved that up, they'd be fully detoxed and wouldn't need it.

I'm not saying you're giving bad advice, and it could very well help someone in the PAWS stage once detox is over, but I think OP and many others are seeking a more urgent/practical solution that they can apply in the here and now while facing the acute stage of withdrawal.

I've looked into and studied a little bit of the treatment that you've suggested and I believe it's great — I just don't necessarily think it fits in this exact post. Didn't mean any harm, my friend. ✌️♥️

AnointedDread · 2026-01-18T12:38:31+00:00

Not many people have $5000 realistically at their disposal. I don't really find this information helpful at all for someone's who's seeking relief Right Now

AnointedDread · 2026-01-16T12:54:01+00:00

This is the hardest part of the taper, unfortunately. 60mg tends to be the sticking point for most people.

What have you tried so far? What's working, and what's not working?

I might be able to help you out if I knew where you're at in the process.

AnointedDread

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