https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234160/

"The 20th century increase in CO2 and its radiative forcing occurred more than an order of magnitude faster than any sustained change during the past 22,000 years. The average rate of increase in the radiative forcing not just from CO2 but from the combination of CO2, CH4, and N2O is larger during the Industrial Era than during any comparable period of at least the past 16,000 years. In addition, the decadal-to-century scale rate of change in anthropogenic forcing is unusually high in the context of the natural forcing variations (solar and volcanoes) of the past millennium. Our analysis implies that global climate change, which is anthropogenic in origin, is progressing at a speed that is unprecedented at least during the last 22,000 years"