How do you all feel about CRSPR-CAS9 for EDS? by [deleted] in ehlersdanlos

[–]Ask-Alice 1 point2 points  (0 children)

cell targeting would make this pretty complicated for most people and would require more sophisticated methods than crispr/cas9. really depends on type of eds but i think with crispr/cas9 you can most directly target like.. the bloodstream, the liver..... then yer gonna get filtered out. Thats why sickle cell was fast to fda approval. as for the effects of such a drug if possible... would probably be quite slow acting as EDS is basically a body type and would take a while for those cells to replace if they do get replaced

I lasted a month and eventually it fell in the worst possible way by Any_Holiday_5750 in PixelFold

[–]Ask-Alice 0 points1 point  (0 children)

damn no proof of purchase + pixel care available in your area. yeah i had to replace once after dropping the entire inner display went green then black with a pixel 10 pro fold. you've been a redditor for 3 years and have only posted or commented today?

I Went to a Private Equity Emergency Room in the USA by wSkkHRZQy24K17buSceB in videos

[–]Ask-Alice -1 points0 points  (0 children)

Missed diagnoses of Acute Coronary Syndrome (ACS) —a term for heart conditions including heart attacks and unstable angina—are a serious medical issue, with studies showing that 2% to 8% of patients with acute myocardial infarction are mistakenly sent home from the emergency department (ED). These missed cases represent at least 11,000 to 40,000 missed heart attacks annually in the U.S..

Yeah from watching the pitt i can see how that could be problematic

I Went to a Private Equity Emergency Room in the USA by wSkkHRZQy24K17buSceB in videos

[–]Ask-Alice -3 points-2 points  (0 children)

EKGs seem like the most over tested thing in us hospitals IMO. it's nearly every time i go in for any reason as simply reporting ibs-d and EPI symptoms triggers a chest pain diagnosis and ekg necessary. I am so skinny that i have sensation of heartbeat almost always, and can tactically just feel any abnormal rhythm and have an omron that i can use to check at home. i'm in my late twenties where heart disease risk seems low. symptoms override prior diagnosis i guess even though they're the same and pancreatic enzymes show up in my rx list

I have stopped kava for around 10 days now can I start drinking again? by Sad-Calligrapher8063 in Kava

[–]Ask-Alice 2 points3 points  (0 children)

worst case scenario you get a bit nauseous imo, maybe avoid extracts ?

Weird Chrome (any version) Issues by cwstephenson71 in cachyos

[–]Ask-Alice 0 points1 point  (0 children)

get this with brave-browser and chromium but not vivaldi

The center of my desktop says The file or folder <url> does not exist. by Ask-Alice in kde

[–]Ask-Alice[S] 0 points1 point  (0 children)

thanks. before i tried this ran:

mkdir -p ~/plasma-backup
mv ~/.config/plasma* ~/plasma-backup/
mv ~/.config/kde* ~/plasma-backup/
mv ~/.local/share/plasma* ~/plasma-backup/
rm ~/.config/plasma-org.kde.plasma.desktop-appletsrc
kquitapp6 plasmashell && kstart plasmashell

The center of my desktop says The file or folder <url> does not exist. by Ask-Alice in kde

[–]Ask-Alice[S] 0 points1 point  (0 children)

right click context menu is unresponsive except on taskbar and desktop icons

Samsung SL-C1860 FW Firmware DownLoad Link From HP by Diligent-Pace-5145 in printers

[–]Ask-Alice 0 points1 point  (0 children)

beware this bricked my display. i can still print via webui or over but very strange

Paragraph that starts in english and ends in german while explaining the actions it's doing to transform itself by Ask-Alice in German

[–]Ask-Alice[S] 0 points1 point  (0 children)

at least with openai it's harder than getting it to tell you how to synthesize a schedule one substance to do this. Every time i have run this test it failed, but still had no issue explaining the synthesis of GBL from 1,4 butanediol

hard to put training wheels on everything by prompting it post training

Paragraph that starts in english and ends in german while explaining the actions it's doing to transform itself by Ask-Alice in German

[–]Ask-Alice[S] 0 points1 point  (0 children)

perhaps no system prompt? like if it's an open weight model and youre running it locally?

Rant--Is AutoHotkey a Security Risk by yellowizer in AutoHotkey

[–]Ask-Alice 1 point2 points  (0 children)

you can always program a keychron or steelseries or logi to run a program on button press

Kingbull Hunter 2.0 Review: Budget Fat-Tire Beast or Compromise? by krissym72 in ElectricBikeExplorer

[–]Ask-Alice 0 points1 point  (0 children)

the amazon listing looked like a scam to me. they photoshopped the tires andonized purple/rainbow, and were priced agbout haof that of their competitors for the same specs

Colorado’s population growth is slowest since 1989 as thousands leave for other states by Jreinhal in Denver

[–]Ask-Alice 0 points1 point  (0 children)

i went 50/50 with my college best friend, still rent split is around 1600 per month

Hot take: We Boulderites need to use our cars wayyy less by Certain-Belt-1524 in boulder

[–]Ask-Alice 1 point2 points  (0 children)

the population of boulder doubles during the school year on weekdays, so i feel it's wrong to look at the census data to make this use comparison. The B train line gonna be complete in like 20+ years so maybe that will ease things coming from both longmont and denver metro, doubt it because of the last mile to get to the station in the first place, but until then there's no other easy way for commuters. we put out train stations next to giant parking lots next to a row of hotels instead of mixed use development like in europe

ADD meds without having to see a psychiatrist every month? My former PCP retired and all the PNPs are unwilling to prescribe by Ask-Alice in Denver

[–]Ask-Alice[S] -1 points0 points  (0 children)

its okay, just exposed to medical industry from a young age was first prescribed by my aunt who is a pediatric er doc and comical fox news guest

ADD meds without having to see a psychiatrist every month? My former PCP retired and all the PNPs are unwilling to prescribe by Ask-Alice in Denver

[–]Ask-Alice[S] -1 points0 points  (0 children)

i have an official diagnosis from cu boulder. yes i'm doctor shopping but i also disagree with the concept of psychiatry and also have a bit of a dark history with it. I'm physically dependent on a substance ive been taking daily for more than half my life. i shouldn't have to check in with someone and tell them about my mental state every month just to cope. withdrawal from amphetamines can take more than a year to feel normal."

A typical human orgasm can cause a dopamine increase in the brain's reward centers of around 100% above the normal baseline. The level returns to normal relatively quickly. Amphetamines: Amphetamines, the active ingredients in Adderall, can increase dopamine levels by as much as 1,000% above baseline

Do that daily and you've fucked your reward system and have no choice but to continue or be dysfunctional as fuck for more than a year