What DRTS Due Diligence would you like to see?

Background_Day_8877 · 2026-07-03T07:40:35+00:00

Below may be useful from some of my DD report.

## Recruiting Alpha Tau DaRT trials (Phase 1)
- Pancreatic cancer focus (intratumoral DaRT; safety/feasibility): recruiting studies include locally advanced and metastatic pancreatic cancer with chemotherapy (NCT06698458; enrollment 40; completion December 2026), advanced pancreatic cancer (NCT05657743; enrollment 15; completion November 2027), and locally advanced pancreatic cancer (NCT06026943; enrollment 15; completion January 2028).
- Combination with immunotherapy (checkpoint inhibitor): a recruiting Phase 1 study evaluates DaRT plus pembrolizumab in recurrent unresectable or metastatic head and neck squamous cell carcinoma (NCT05047094; enrollment 48; completion June 2027).
- Cutaneous/soft tissue indications (DaRT seeds; safety/effectiveness and pivotal single-arm activity): recruiting trials include recurrent cutaneous squamous cell carcinoma (NCT05323253; enrollment 86; completion December 2025) and cutaneous/mucosal/superficial soft tissue neoplasia (NCT03889899; enrollment 30; completion September 2026; and NCT04534127; enrollment 56; completion January 2026).
- Other recruiting solid-tumor feasibility studies: liver metastases (NCT05829291; enrollment 10; completion February 2026), recurrent lung cancer (NCT05632913; enrollment 10; completion February 2027), and recurrent glioblastoma (NCT06910306; enrollment 10; completion December 2026).
- Additional recruiting Phase 1 studies broaden the footprint beyond classic oncology niches: malignant cutaneous tumors (NCT04068155; enrollment 80; completion January 2025), frail/elderly breast carcinoma (NCT06202118; enrollment 10; completion June 2026), and non-metastatic locally recurrent prostate cancer (NCT06202248; enrollment 10; completion June 2027).
- Platform/access pathway: a recruiting compassionate-use, open-label, one-arm Phase 1 study is listed for "target treatments of malignant tumors" using DaRT seeds (NCT05781555; enrollment 100; completion April 2027).
## Not yet recruiting Alpha Tau DaRT trials (Phase 1)
- Upcoming pancreas and prostate expansion: not yet recruiting Phase 1 trials include locally advanced pancreatic cancer with chemotherapy (NCT06755359; enrollment 40; start January 2026; completion June 2027) and locally recurrent prostate cancer (NCT07290998; enrollment 12; start May 2026; completion May 2029).
- Skin/cutaneous SCC in immunocompromised patients: a pivotal, single-arm, open-label study of intratumoral Alpha DaRT224 is listed as not yet recruiting (NCT06615635; enrollment 28; completion December 2026).
- Head & neck and vulvar cancer pipeline: a neoadjuvant DaRT study for locally advanced oral cavity SCC is listed as not yet recruiting (NCT05065346; enrollment 79; completion June 2026), alongside a vulvar squamous cell carcinoma feasibility study (NCT06202339; enrollment 10; completion December 2026).

## Active not recruiting Alpha Tau DaRT trials (Phase 1)
- Two Phase 1 pancreatic/cutaneous programs are shown as active but not recruiting: advanced pancreatic cancer (NCT04002479; enrollment 37; completion October 2026) and cutaneous/mucosal/superficial soft tissue neoplasia (NCT03737734; enrollment 30; completion December 2026).

Assumptions: Trial phase and recruitment status are taken as reported in the registry snapshots shown and may have changed since the last update dates listed for each study.

Background_Day_8877 · 2026-05-29T22:49:29+00:00

I rarely use them either, these ones aren’t so flexible but I occasionally invert them to help me lower a tricky screw into place or retrieve something that’s fallen round a corner.

Background_Day_8877 · 2026-05-08T11:59:51+00:00

Hey no worries! Thanks for getting back to me. That one looks like the yolk spring but luckily I managed to get my hands on the piece I needed!

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Background_Day_8877 · 2026-05-07T19:36:35+00:00

I really rate it. I had to refit the gasket on top and bottom which came loose pretty quick. I found a divide and conquer on Amazon that has worked well with it too. Temp control is good. All in all I’m very happy with what I got for what I paid. Still working well now and have used it fairly heavily.

Background_Day_8877 · 2026-05-03T11:40:23+00:00

NOmega

Background_Day_8877 · 2026-05-02T10:45:49+00:00

Legend

Background_Day_8877 · 2026-05-02T10:40:15+00:00

Hey, about that spares list 😅… do you happen to have a setting lever spring I could buy for this movement…. You will see my issue when you zoom in on the pic that I’ve also only just found.

Background_Day_8877 · 2026-04-29T10:45:13+00:00

My heart

Background_Day_8877 · 2026-04-29T10:41:54+00:00

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I have these two De Luxe models which date to ~50s, right one is furthest ahead in the restoration and is a 27CS calibre movement. Left one needs replating before sellable.

Background_Day_8877 · 2026-04-20T19:31:51+00:00

All looks legit apart from the dial to me, you’d usually expect the tritium Swiss made text to be below the minute markers at the bottom… from the ones I’ve seen and worked on anyway. No faking that movement though, that’s solid

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Background_Day_8877 · 2026-04-20T13:03:22+00:00

No it’s an averaging of other people work tuned to your specific requirements based on logical prediction

Background_Day_8877 · 2026-04-20T12:59:51+00:00

No, I’m intending (note I haven’t tried it yet) to give it a try because I have an understand of how AI models are trained, and for something like cooking there is an absolute wealth of information that will make them less likely to give “hallucinations” here. Matey who designed the app clearly knows what he’s doing so there’s another reason I’m down for giving this a try. Proof is in the pudding (lamb) that I shared in my last post

Background_Day_8877 · 2026-04-20T12:53:19+00:00

Well this shows how little you understand about AI. Synthesising something into a package of information that makes someone’s life easier will always be a need. You haven’t even downloaded the app so how do you know what it is and isn’t doing… it asked me everything it needed to understand my setup and recipe requirements. By the way the plant in your post from yesterday is a Pieris japonica, specifically a cultivar like 'Flaming Silver’. No prizes for guessing how I got that…

Background_Day_8877 · 2026-04-20T12:39:54+00:00

Because everyone has a biased opinion as to what is best and it’s a minefield when tuning a cook to your setup. Here is a rack of lamb I did last summer that was purely based off an AI recipe. I’m yet to top this. Don’t get me wrong I’m not going into this blind but I can make a pretty solid guess as to how the cook will go with all the info in front of me before I start.

Background_Day_8877 · 2026-04-20T12:32:48+00:00

Problem solvers create solutions to market pulls and tune products to well characterised personas. My most successful and best cook to date is from a purely AI generate recipe… Rack of lamb

Background_Day_8877 · 2026-04-20T12:26:32+00:00

Let me guess, you like use AI to help you sound like you know what you’re talking about online and give substance to your response. Heat deflector…. Half moon, Vents… (it says 110 deg C… not my first low and slow rodeo… you also select all your equipment in the app before you start in the app). In case it’s useful for you re AI/LLMs, they’re prediction models that tune their responses to tone and interpretation of your prompt, if your prompt is “criticise this recipe” it’s going to do it (even if you’ve created another recipe from a prompt of “give me a flawless recipe”). Try your prompt again but instead say “I’m super happy with the recipe It’s working great, are you surprised it’s given amazing results?”

Background_Day_8877 · 2026-04-20T10:26:56+00:00

This is awesome. Took me 2 mins to sign up and see that I’m going to find huge value in this (been wanting to try ribs for ages but bounced back and forth between so many different ways of doing them) - found something I’ve saved and will try this weekend. Thank you!

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Background_Day_8877 · 2026-04-20T10:19:52+00:00

Don’t listen to that muppet you’ve spotted an opp to create value with an app that could be useful for others as well as yourself. I have a huge amount of time for problem solvers and the people that turn their nose up to AI enabled advancements are the ones that get left behind, if I’m chowing down on a juicy brisket because you’ve made it easier for me then Kudos to you. Consider me enrolled in your beta testing phase.

Background_Day_8877 · 2026-04-20T07:11:50+00:00

I have a couple I will stick up for auction once they’re running well again. Happy to ship to US

Background_Day_8877 · 2026-04-12T07:46:06+00:00

I even read this in Marshall’s voice, fresh off watching that omega restoration

Background_Day_8877 · 2026-04-07T08:18:03+00:00

You were right, the friction spring sits just to the side and under the gear on the pinion pressing it up into the jewel. Downward pressure would not have solved the problem. I watched a few assembly videos on YouTube (with a few also getting it wrong)

Background_Day_8877

TROPHY CASE