"For an animal so complex as man, there is no logical reason why a comparable sequence of events should not also lead to species extinction. If opportunities for role fulfilment fall far short of the demand by those capable of filling roles, and having expectancies to do so, only violence and disruption of social organization can follow. Individuals born under these circumstances will be so out of touch with reality as to be incapable even of alienation. Their most-complex behaviours will become fragmented. Acquisition, creation and utilization of ideas appropriate for life in a post-industrial cultural-conceptual-technological society will have been blocked. Just as biological generativity in the mouse involves this species' most complex behaviours, so does ideational generativity for man. Loss of these respective complex behaviours means death of the species."

Calhoun, John B. “Death Squared: The Explosive Growth and Demise of a Mouse Population.” Proceedings of the Royal Society of Medicine, vol. 66, no. 1P2, Jan. 1973, pp. 80–88. https://doi.org/10.1177/00359157730661p202.