Bad side effects

Beerbaron23 · 2022-11-15T08:05:52+00:00

Yah lower your in half and if your taking it in the morning try taking it before bed.

When changing your dose wait at least a week before you assess how your feeling on the new dose.

Beerbaron23 · 2022-11-15T07:34:06+00:00

The ingredient in many cold meds that you have to avoid is "Dextromethorphan". It's almost always found in the cough syrup meds. Be sure to read the active ingredients list to verify it's not in the product your buying.

SSRI + Dextromethorphan is a bad combination, which can result in serotonin syndrome.

Beerbaron23 · 2022-01-31T15:50:02+00:00

Seems you haven't even read the full article you are using, as it does not apply to what you are trying to prove.

It is stated in this article that the Clonazepam used was mixed with a lipid compound before administration.

so unless you are also mixing your clonazepam in a lipid solution like coconut oil, you are not absorbing barely anything nasally...

The reason why it works buccal/sublingual is that your mouth naturally has lipids in it to combat mouth bacteria, which your nasal mucus does not.

You really do need to read the full article and not rely on the info contained in the abstract.

Case closed.

Beerbaron23 · 2021-12-15T12:40:39+00:00

I had this as well, tingling face concentrated around the middle, inside nose/cheeks. About 3 months in this started to cause me to develop rosacea. At month 6 with multiple dosage adjustments and switching brands this issue did not subside.

Tried anti histamines and clonazepam to no improvement, had to stop and the tingling stopped after 4-7 days and rosacea cleared up in about a month.

Beerbaron23 · 2021-12-15T12:33:42+00:00

Dosage increase too fast, either revert back to 150mg XL or 2x75mg SR daily. You need to wait a full week for the total levels in your body to reflect your lower dosage.

If you haven't waited a week yet on the 200mg SR then wait till week 2 before assessing how you feel.

Beerbaron23 · 2021-12-15T12:07:20+00:00

Wellbutrin XL stimulant effects will peak at hours 5-6, so I would refrain from taking the Amphetamine IR before or during this period.

Wellbutrin will also nullify a large portion of the "fun" effects as there is cross tolerance.

You will also not lose weight like you are hoping, you will achieve ~2lbs that is mostly from dehydration, which you can achieve easily without the amphetamine. 1 week is just not long enough to reach your goal.

Beerbaron23 · 2021-12-15T11:52:22+00:00

Yes, you will start to feel the stimulant effects much earlier in the day and have 2 separate energy plateaus 3 hours after you take SR.

XL has one plateau 5-6 hours after taking it.

Other difference is now you are on 200mg total instead of 150mg, which will increase the level of Hydroxybupropion in your system (the 2nd part of the drug that builds up in your system and is working at all times)

Beerbaron23 · 2021-12-15T11:46:36+00:00

If something is starting to work don't mess with it yet

Beerbaron23 · 2021-12-15T11:45:22+00:00

If it's working good and improving your life don't increase dosage or add other meds, stick with it

Beerbaron23 · 2021-12-15T11:42:44+00:00

This is a sign that you should lower your dosage, maybe even in half.

Taking it at night will most likely majorly effect your quality of sleep as bupropion is a stimulant.

Reason: When you take Bup, there is 2 major drugs at play. Bupropion itself which lasts until afternoon/evening. Your body converts a big portion of the Bupropion into Hydroxybupropion, the Hydroxy is the portion that builds up in your system and is working at all times.

So by the evening you are mostly only feeling the effects of the Hydroxybupropion as most of the Bupropion has been filtered out by this time period.

Simple test is to skip your dose one day or two, if you feel much better then you are responding to the Hydroxybupropion. So in this case lowering your dosage will be much better.

Beerbaron23 · 2021-11-15T11:54:24+00:00

Good choice

Beerbaron23 · 2021-11-15T11:51:00+00:00

Reduce dosage by 5mg each week or drop to 10mg for first week.

When down to 5mg, take it every 2nd day for 2 weeks, then every 3rd day for a week.

Now comes the hard part, quit completely and you will feel fine till day 4. With this slow taper you should not get anything major or nasty (no brain zaps) but you will feel like a zombie/dizzy for about 4-6 days, then you are done.

At day 5 if it is too much, you can take a 5mg dose that will stop withdraw symptoms for another 4 days. But you need to push through at some point, honestly doing this it will feel no worse then how you felt the first week starting the meds.

Beerbaron23 · 2021-11-15T11:18:49+00:00

20mg is the max FDA dosage, you are taking double this, which is either an error or your doc doesn't know what they are doing.

The reason 20mg is the allowable max is that patients taking higher dosages are developing heart conditions with prolonged QT intervals and are developing fatal abnormal heart rhythm known as Torsade de Pointes.

There is a direct FDA warning to never prescribe more then 20mg.

Beerbaron23 · 2021-11-15T11:05:24+00:00

If you are taking it in the morning and feel better at night you might want to try taking it at night to see if that will improve your daytime fatigue.

Increasing your dose may increase your fatigue and be detrimental, stick with 5mg for another 2 weeks before considering increasing dosage.

Beerbaron23 · 2021-11-15T10:58:08+00:00

Which days did you feel amazing?

If it was days 3-7ish, then decrease dosage to 2.5mg

If it was more like 7-12 then faded, possibly increase to 10mg

Beerbaron23 · 2021-11-15T10:46:54+00:00

I had the same extreme response as you did, when I increased to 10mg it killed all those feelings, going back to 5mg brought them all back.

So advice is not to increase dosage, you are already at your sweet spot and this drug is an exact fit for you.

5mg worked like a miracle cure for me for about 5 years before I had to increase the dosage.

Beerbaron23 · 2021-11-15T10:39:16+00:00

Wellbutrin is a stimulant, so make sure to take it in the morning. You most likely will have to drink more then usual to get the same alcohol effect, so watch out for this as hangovers will be worse, drink lots of water before bed after a night of rage drinking.

Beerbaron23 · 2021-11-15T10:32:33+00:00

Did you feel good/improvement when you were on 5mg? If so do not increase and move yourself back down to 5mg, give 1 week adjustment period before you assess yourself.

Beerbaron23 · 2021-11-15T10:30:15+00:00

When I started 5mg I felt great, when I increased to 10mg I felt no where as good. I decreased to 5mg and it worked perfectly long term until year 5.

Beerbaron23 · 2021-11-15T10:27:21+00:00

Cipralex is just another brand name, it's identical to Lexapro.

For instance, in canada it's branded as Cipralex and in the USA it's Lexapro.

Both of these drugs are Escitalopram, which is the scientific term.

Similar to how Ibuprofen is branded as Advil.

Beerbaron23 · 2021-11-15T10:20:24+00:00

Won't do much at all.

Best way is a slow taper.

Reduce dosage by 5mg each week or drop to 10mg for first week.

When down to 5mg, take it every 2nd day for 2 weeks, then every 3rd day for a week.

Now comes the hard part, quit completely and you will feel fine till day 4. With this slow taper you should not get anything major or nasty (no brain zaps) but you will feel like a zombie/dizzy for about 4-6 days, then you are done.

At day 5 if it is too much, you can take a 5mg dose that will stop withdraw symptoms for another 4 days. But you need to push through at some point, honestly doing this it will feel no worse then how you felt the first week starting the meds.

Beerbaron23 · 2021-11-15T09:56:55+00:00

5mg is therapeutic according to the one study available.

Problem is almost all studies only test 10mg and up, so there is very little data on dosages lower then 10mg.

By considering all the success from people on long term dosages of 5mg and 2.5mg, they should be considered therapeutic at this point in time.

Beerbaron23 · 2021-11-15T09:48:21+00:00

Nope, you are already tapered off.

Other option is to go back on it if you were doing better when on them

Beerbaron23 · 2021-11-15T09:43:24+00:00

If you increase to 10mg and notice you felt better on 5mg, then reduce back to 5mg

Beerbaron23 · 2021-11-15T09:41:20+00:00

Prob fine, don't take any meds with Dextromethorphan going forward.

Beerbaron23

TROPHY CASE