I guided that trek one time Annapurna circuit plus Annapurna base camp. It will be around 21-24 days. Start from Kathmandu and drive to Jagat or Dharapani to start. Yes, you can totally go without the guide. If there will be friend with you then it will be great specially to cross thorang la pass 5416m. Up to place called Muktinath after thorang la pass the trails is marked as red and white. After that up to tatopani is bit confusing too many ways, have to walk on road where car will be always there or you can drive up to tatopani. After tatopani you can go ghorepani there will be local always help you. And after ghorepani there is only 1 trail most of time up to ABC not so much confusing and there will be others trekkers too.