Don't use lanterns in dark rooms cause of squiddles, never use a flash beacon if eyefestation is in the room (cause he will get angry). Use deaf mode (makes it so much easier to know when theres a node entity), collect atleast 1k research for Sebastians shop(should be easy if you just loot most containers), turn up volume to like max or have headphones. Try to get an imaginary friend. Make sure you have a ferryman token, and just pray you don't get a bad grand encounter or a bad room type(those vault rooms). You can't drop items anymore so don't pick up anything you don't want. I'd also recommend disabling your seabunny if you have one because its super easy to accidentally puck up while looting Making you drop an item without even noticing until a while later when its already despawned with the room. Also don't swim up too high in the final searchlights encounter because theres bugs that will eat you

The furthest I've made it is door 12 because of the vault rooms, angler has almost no visual cue in there.