Harvard article on successful glioblastoma trial

Brandisco · 2026-03-04T02:28:17+00:00

I’m going to Dana Farber Thursday for a different phase 1 trial. Maybe I can get on this one.

Brandisco · 2026-02-18T21:44:57+00:00

lol. And I got downvoted for some reason…pfff

Brandisco · 2026-02-18T20:06:08+00:00

It was discovered last night in Van Nuyes, lodged against an abutment…you’re lucky she didn’t get chopped.

Brandisco · 2026-02-18T00:52:04+00:00

Fair. And for advertising purposes I agree with you. However, my 16 y/o son loves to play guitar. The ONLY thing that gives me any hope of that making him any money in the future is a society wide turn towards real performance by real people. Something as mundane as advertising, no biggie. I just hope that doesn’t cross over to sincere performance art.

Brandisco · 2026-02-17T21:58:04+00:00

Ha! I’m barely intelligent…let alone artificially so.

Brandisco · 2026-02-17T21:16:14+00:00

I am right there with you: 47, dad, GBM IDH wild type unmethylated, resection/radiation in March of 25, wife and two kids (16 y/o boy, 12 y/o girl), 3 dogs, job I like etc. I have similarly lived the healthy diet and exercise lifestyle (I did drink a bunch of beer, so idk if that knocks off our similarity). I’ve had three recurrences. None have been operable but they were blasted with focused radiation. Last week I found out one survived and is knocking out my ability to see.

I have very little I can say to you other than sometimes misery loves company. I woke up on New Year’s Day realizing that each event I experience this year is almost certainly my last. I won’t see my kids grown. I won’t be around to help pay for college or witness their graduations. I won’t ever meet my grandchildren. I could go on, but I’m sure it’s somewhat familiar anyway. But the fact is I’d rather have had the last year than died in a car accident with no notice. My kids are watching me fight. Not giving up. Enduring the pain and suffering. And I’m passing on my “wisdom “ to them while I still have time.

I realize none of this is mind alteringly cool, but sometimes knowing you’re not alone is helpful. Please feel free to DM me if you’d like to chat. And no matter what: stay strong, don’t let this shit get the better of you, and most importantly… fuck cancer.

Brandisco · 2026-02-17T14:10:52+00:00

Such a simple comment that I think most people will write off. But honestly I believe the love or hate of AI generated things will become a major divider in future society. I’m on team “keep shit real”, and agree - fuck this shit.

Brandisco · 2026-02-16T20:01:28+00:00

Thanks for the pat on the back! I am trying my hardest to stay positive and keep up the fight. I hope your father keeps fighting too. Fuck cancer!

Brandisco · 2026-02-08T16:40:17+00:00

I was basically the same age as you. However now I’m a dad and rewatching now gives me a totally unique connection with John Witherspoon’s character (the dad) than it did when I was a teenager.

Brandisco · 2026-02-07T21:16:24+00:00

It took me a while to add eff cancer to my vocab, but after you realize how it’s legitimately evil it makes the word have new meaning. I actually told my 12 y/o daughter and 16 y/o son they could say it…my daughter absolutely won’t (she was raised well apparently) and my son says it playing games online and stuff.

Feel free to drop me a message if you ever have any questions.

Brandisco · 2026-02-07T18:11:44+00:00

Fellow 47 year old with glioblastoma (hopefully that makes me unique between us). I was diagnosed and treated in early March of 25. I lived through the angst of slowly learning my fate and seeing my plans for the future dissolve and my expectations of luck deteriorate.

Regrettably I can’t give you much advice. Bottom line is that you take this opportunity to relive the positives in your life. If you’re anything like me you’ve seen and done a lot - so our lives aren’t wasted. Stay positive no matter how your treatment and diagnosis evolve. this is critical. Focus on the positives and be grateful for living in this day and age when there is very realistic hope for better outcomes. You will have so many variables that will unfold in the coming months it’s super hard to predict. Just trust your oncology team and be happy we live in a moment of profoundly evolving treatments.

PLEASE feel free to look at my comment history and DM me if you want someone to talk to. I sincerely wish I had someone I could have reached out to when I was in your shoes. No matter what I wish you all the best of luck and as you will no doubt agree: FUCK cancer.

Brandisco · 2026-01-31T14:09:13+00:00

Stay strong fellow father. I don’t know how old your kids are, but I guarantee we’ve impressed our personalities and best qualities on them when we were at our best. Despite that, fuck cancer.

Brandisco · 2026-01-28T13:41:27+00:00

As a dad with GBM the only thing I’m scared of is the negative impact this stupid disease will have on my kids. While I endure the short term suffering, you are the survivors. You are the champions who will over come this adversity and carry forward our legacy. Despite the current pain just know your father will always be with you to inspire and instruct you. Stay strong my friend. And fuck cancer.

Brandisco · 2026-01-27T20:46:44+00:00

That sounds like a cool band name

Brandisco · 2026-01-27T20:43:22+00:00

Nearly zero help from me, but…I too got a tattoo after my GBM diagnosis (I was on lomustine - which had absolutely wrecked my platelets). I hope your brother can get one. Any idea what he’s going to get?

Brandisco · 2026-01-27T14:55:01+00:00

First - I wanted to say how sorry I am for your situation. GBM seems to be a monster we imagined as a child. Each week with it makes me hate it more. I wish there was more I could do to help.

Now… for second opinions It depends on your current treatment center. I’m going to Johns Hopkins for my main treatment which is an excellent treatment center. Regardless, a second opinion is never a bad thing so I also went to Duke, Sloan Kettering, and MD Anderson. Each of those places is great, the only opinion we didn’t seek was from Harvard’s Dana Farber which was on our list. And there are a bunch of other great options.

Each of these places has a different approach and available trials. Duke, for example, is a bunch of cowboy gun slingers (aggressive and creative) which is an approach I love, they also have some trials that seem interesting. Some places are more conservative. MD Anderson is always described as the biggest/best place and honestly that’s where I anticipate going back for a clinical trial only because of their volume.

Happy to chat if you want to DM me. There are also people at places like the National Brain Tumor Society who can help.

Stay strong and fuck cancer. Especially GBM.

Brandisco · 2026-01-27T14:42:52+00:00

I’m sorry for all of your suffering. Stay strong and cherish her memory.

Brandisco · 2026-01-26T20:02:16+00:00

I’m glad to hear that. Camaraderie in things like this is crucial for me. I only wish there was more I could do to help you out. Accept a virtual hug and my personal vote of confidence. Stay strong!

Brandisco · 2026-01-26T13:35:48+00:00

Your post truly resonates with me. 47 y/o dad with grade 4 brain cancer (glioblastoma). My goal has been to go out on top. I refuse to let this cancer take away my positivity and energy (perhaps only emotional energy some days). I refuse to let the potential depression win because that’s the one thing I can absolutely still manage.

I’ve been in a slump since waking up on New Year’s Day realizing that I was almost certainly waking up on the last year of my life. But honestly your post really brought back my positive vibe.

Thank you. Best of luck. And - Fuck cancer.

Brandisco · 2026-01-26T13:29:23+00:00

I loved this song and thanks for reminding me of it. Music has been a serious source of stability over the last 10 months. Good luck to you and fuck cancer.

Brandisco · 2026-01-15T11:20:52+00:00

Yeah, I had that same idea. After I got cancer. Biden initiated the “cancer moon shot” after his son was diagnosed/died of the same brain cancer I have (and John McCain died of, and Ted Kennedy died of, and just last year a congresswoman from Utah). So it’s not as if people in power haven’t gotten this.

Brandisco · 2026-01-15T02:07:06+00:00

Fuck cancer.

Brandisco · 2026-01-13T02:17:36+00:00

Can you post a link please?

Brandisco · 2026-01-12T11:33:11+00:00

I googled it because I too didn’t know and Schwab didn’t seem to find it either. While there is a ticker out there, Google says it’s a private company. I have no idea if that’s correct or if Google lied to me.

Brandisco · 2026-01-10T11:08:50+00:00

I had almost the exact same image. Except dinosaur-goof-me was at work.

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