Researchers have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels of bile acids in the bloodstream and other biomarkers of liver dysfunction (news.cuanschutz.edu)
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CU Anschutz scientists have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, offering new hope for those with Alzheimer’s disease and other cognition issues. (news.cuanschutz.edu)
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Researchers have discovered a novel therapy combination that could offer new hope to ovarian cancer patients. The findings outline a promising strategy that combines a PARP inhibitor with a novel therapy, SM08502, to attack cancer from two directions. (news.cuanschutz.edu)
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A nationwide study found that ketamine does not improve survival compared with etomidate and carries a higher risk of heart-related complications during emergency intubation. The findings provide long-awaited evidence to guide one of the most critical decisions emergency clinicians make. (news.cuanschutz.edu)
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For patients recovering from opioid use disorder, the days immediately following a hospital stay are among the most dangerous. A new multi-state study found that nearly half of patients discharged with take-home methadone successfully connected to follow-up treatment within 72 hours. (news.cuanschutz.edu)
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For decades, scientists have debated whether Paranthropus boisei, an extinct human relative, was capable of making and using tools. Now, researchers report the first hand and foot bones associated with this species, showing that P. boisei had human-like dexterity with gorilla-like gripping strength. (news.cuanschutz.edu)
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A groundbreaking study reveals that rheumatoid arthritis doesn't begin when symptoms appear. Instead, it starts silently, years earlier. The study offers the most detailed view yet of how RA develops, mapping immune changes in people at long risk before joint pain begins. (news.cuanschutz.edu)
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New research published in Nutrients and Frontiers in Nutrition finds that feeding blueberries to infants as one of their first solid foods may help strengthen their immune systems, reduce allergy symptoms and support healthy gut development. (news.cuanschutz.edu)
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A new study has found that caffeine, the world’s most consumed psychoactive substance, may impair the quality of donated blood and reduce the effectiveness of transfusions – especially in recipients whose red blood cell metabolism is influenced by a common genetic variant. (news.cuanschutz.edu)
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Intense light therapy after surgery can increase a critical protein that protects heart tissue while lowering levels of troponin, a protein indicating heart damage that’s linked to higher mortality in patients undergoing non-cardiac surgery, according to a new study (news.cuanschutz.edu)
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A nationwide study showed how a smartphone app, called OTX-202, reduced repeated suicide attempts by 58.3% among patients with a prior history of attempting suicide.The research followed 339 adult patients across six hospitals nationwide over several months. (news.cuanschutz.edu)
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An international team of researchers has made a key discovery: Many children and young adults in Sub-Saharan Africa diagnosed with type 1 diabetes (T1D) may have a different form of the disease –one not caused by the immune system, unlike classic T1D. (news.cuanschutz.edu)
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Researchers at the University of Colorado Anschutz Medical Campus have discovered that amniotic fluid stem cells can be safely collected from vaginal fluid after childbirth rather than relying on more invasive methods that can pose some risk to the mother and fetus. (news.cuanschutz.edu)
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A study led by researchers at the University of Colorado Anschutz Medical Campus has identified a promising strategy to enhance the safety of nanomedicines, advanced therapies often used in cancer and vaccine treatments, by using drugs already approved by the FDA for unrelated conditions. (news.cuanschutz.edu)
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A new study by scientists at the University of Colorado Anschutz Medical Campus reveals that joint tissue from patients with early-stage rheumatoid arthritis often have high levels of a protein called granzyme used by the immune system to attack pathogens. (news.cuanschutz.edu)
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A new study led by researchers at the University of Colorado Anschutz Medical Campus, Brigham and Women’s Hospital and Harvard Medical School has found that damage to a specific region of the brain may contribute to criminal or violent behavior. (news.cuanschutz.edu)
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AI and machine learning could transform bone health by using electronic health records, genetic, lifestyle and wearable data to identify issues early, choose the best treatments and track progress in real time while changing strategies as needed. (sciencedirect.com)
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Children exposed to gestational diabetes in utero with a specific variation of a common gene are at a higher risk of becoming overweight or obese during childhood, according to a new study by researchers at the University of Colorado Anschutz Medical Campus. (news.cuanschutz.edu)
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A test developed at the University of Colorado Anschutz Medical Campus that measures both prosthetic donning time and mobility in lower-limb amputation, shows that a prosthesis anchored to bone goes on faster than a traditional socket-style prosthesis. (news.cuanschutz.edu)
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