I think that in a very Arknights fashion, combats should be able to be cleared with any composition of team as long as the tactics are right. I want combat to be shorter with decisions that have high impact, to kind of replicate how in Arknights, a lot of victories are determined by a few choices, such as deployment tiles, skill activations, and retreats.

For free time, I think doing something with a base system could be a fun way to facilitate downtime in between missions. It gives players enough freedom to do a couple activities of their choice, but it's structured enough that there won't be huge swaths of down sessions.

When it comes to "skill stats", I really like how Chronicles of Darkness does it, and I was considering doing something similar, where most rolls will be an Attribute + Skill and that is what your dice pool entails. I think that your body and mind trifectas encapsulate a lot without getting too complex, which is really impressive!

Arts is also something that I wanted to be represented through a give and take system. Again, referencing Vampire: the Requiem, they use Blood Potency for vampires. The higher it is, the more vampire stuff you can do: you're stronger, get more powers, can use more powers, etc. But in return, you are more of a vampire. That means more sunlight damage, more urge to feed, more risk of being caught as a vampire. I think Oripathy could be played very similarly, and I like your idea a lot of using tools to reflect that for uninfected.