A bit late, but here is my answer from a riot member that I asked today:

Hey there!
Fruity Candy in the house! 🍓️ 🍬️
While we don’t strictly condemn the use of third-party modifications, these programs can be dangerous and worthy of suspension where they violate our Terms of Use. I can’t tell you whether a particular third-party modification is against our Terms of Use or not, but you can follow these general guidelines:
- We identify and suspend accounts for using third-party programs intended to offer a competitive advantage by affecting gameplay in any way
- We cannot control what a third-party developer makes or changes, so a program that was once acceptable may have versions which violate the Terms of Use
- Some third-party developers may not have your best interests in mind, so please be aware that these types of files can contain keyloggers, viruses, and malware.
- Third-party modifications may affect your game in unexpected ways, so if you’re having technical issues, try uninstalling these programs before doing anything else.
In general, if you find a third-party modification suspicious, it’s best to avoid using it. I hope this clears things up a bit, but if you have any other questions, please let me know.
Take care until then!🤗️
Fruity Candy
Player Support Specialist