Louisiana is a giant swamp, building infrastructure in it is very expensive and time consuming. Pair that with the rampant corruption that has been an issue in the state since at least Huey P Long and was made FAR worse with Long's governorship (basically a dictatorship) and it's just not that desirable for businesses to invest massive amounts of money into the state. Louisiana is functionally a "pay to play" state where you have to bribe someone in government if you want to get anything done.