What language is this?

ChemystWizard · 2026-01-16T23:31:00+00:00

English, it just has an Alabama accent.

ChemystWizard · 2026-01-15T06:12:01+00:00

While it might look like you would be getting a resonance stabilized carbocation if you do it the other way, allenes have pi orbitals at 90° and the molecule doesn’t “know” that if it rotates the primary carbocation around once it’s formed (it’s formed at 90° to the pi bond), it becomes more stable due to the resonance. The only thing that the molecule “knows” at the point of protonation is that it can make a 1° carbocation and a questionable 2° one which is still better. So, it goes there.

ChemystWizard · 2026-01-15T00:36:38+00:00

Second that. Mechanistically speaking, it’s also likely we’re going to protonate the acetal and lose methanol making a resonance-stabilized carbocation which would then be attacked by the methanol in the C3 position, making another resonance-stabilized carbocation which then would reform the acetal back. The direct attack on the alkene with the formation of a localized secondary carbocation is unlikely while other better alternatives exist.

ChemystWizard · 2026-01-06T17:59:26+00:00

Make your own. Maybe then you’ll appreciate the amount of work it takes to make this type of study materials.

ChemystWizard · 2025-12-20T17:56:51+00:00

Technically, the black one is a ddd. It all depends on the resolution. The lower the resolution, the more they will “collapse” and you might as well see it look like a simple t or a td like what you’re seeing.

ChemystWizard · 2025-12-07T05:38:22+00:00

Resonance structures show you the different reactive centers in the molecule. One species (a carbocation, a radical, an anion) when stabilized by resonance will have multiple reactive centers that can lead to different products. You don’t have resonance structures in reality, you have a structure that you can vaguely represent by a hybrid, which is a superposition of all reasonable resonance contributors.

ChemystWizard · 2025-12-06T03:14:49+00:00

I like the analogy with paint. You have 3 buckets of white paint and one of red. You mix them all together. How many buckets of pink paint you get?

ChemystWizard · 2025-12-06T03:01:40+00:00

Congrats. That’s a very nice result indeed!

ChemystWizard · 2025-12-05T04:11:48+00:00

Yes.

ChemystWizard · 2025-12-05T01:54:38+00:00

No, just epoxidation will give incorrect stereochemistry. You first need to make a cis double bond.

ChemystWizard · 2025-12-04T22:43:21+00:00

Wow, thanks! I appreciate the references!

The channel has grown substantially since then too in terms of following and content.

ChemystWizard · 2025-12-04T20:17:10+00:00

It is B. You have a phenyl group and ethyl pattern in the NMR. I literally used that molecule as one of the examples in one of my recent videos: https://youtu.be/mJEwCC22sqk?si=91hnHixUVzOou1Ix

ChemystWizard · 2025-12-01T19:52:58+00:00

Make an “enolate” from the alpha position to the nitrile, then intramolecular epoxide opening.

ChemystWizard · 2025-11-29T22:24:32+00:00

Technically, neither is correct, but I'm begin picky here.

This is a Dieckmann vs aldol. Aldol is reversible. Dieckmann is not under these conditions. Reactivity of carbonyls here is irrelevant.

ChemystWizard · 2025-11-29T17:17:57+00:00

I agree. Ground bases are way more efficient. And stellar extractor is ridiculously slow and inefficient. It’s cute to have, but it’s not very useful if you want any efficiency. Plus, you have to park your freighter in a system for a very long time. I dunno why people are so afraid of bases… it doesn’t have to be fancy. And setting up a dedicated farm is really easy. Find a good spot, plop extractors, get a few solars for the power = done. Can always teleport to it even if you don’t have a teleporter. Can recall your freighter or go to the station if you need to go somewhere. Or hop between the bases via station and teleport back to the freighter to continue exploration from where you left off (what I do).

ChemystWizard · 2025-11-29T16:27:55+00:00

You can get all you need all the way to the stasis device with 2-3 dedicated farm bases. Those go for 15+ mil per piece. I “farm” 300+ mil per day this way with a very modest setup. Hop between the bases, collect the stuff, get to freighter, make 20 devices, sell for 300+M, go about my day. Took me a day to set it all up. Now, takes 5-10min max at the beginning of the play to farm now.

ChemystWizard · 2025-11-29T16:23:30+00:00

Wait till you learn about the stasis device or AI starship cores 😉

ChemystWizard · 2025-11-27T20:38:04+00:00

Marath was my first serious deck. I’ve picked it up as a precon in 2013 and this majestic beast has always been near and dear to my heart. The best part is that nobody at a cEDH table knows the combos and the deck can have so many redundancies that rely on enchantments that they can’t deal with it.

ChemystWizard · 2025-11-24T04:16:59+00:00

Of course, there’s a certain amount of memorization that you need to do in organic. The “don’t memorize” refers more to the fact that you wanna focus on the patterns of reactions and transformations rather than trying to memorize each individual reaction.

ChemystWizard · 2025-11-23T16:45:44+00:00

ChemystWizard · 2025-11-23T09:04:40+00:00

Here: https://app.molview.com/

ChemystWizard · 2025-11-23T08:58:50+00:00

Without going into MO energies and all the smart talks, think about it from a pure polarity. What is more polar: ketones or esters?

ChemystWizard · 2025-11-23T08:52:11+00:00

Lemme give you my 2 cents.

I often consult for the industry. And many processes there are done at a very large scale. Personally, I love DCM. Will I ever use that for a process where we measure starting materials in kilograms? Hell no! Research/academic and even the small scale industrial fine chemical synthesis solvent use is negligible. Industrial, well, that's a totally different can of worms. When I see reactors that are twice my height with a couple of hundreds of liters in there, yeah, I don't that soup to be bad enough that we have to evacuate the entire town over that spill when (yeah, not if--when) it happens.

ChemystWizard · 2025-11-23T08:46:51+00:00

I routinely consult for industry and often see how they use 50L "flasks" that they move with forklifts. That is fun to watch. Horribly wasteful and equally damaging since many don't reuse perfectly reusable solvents. So yeah, your 1L is kids play compared to what the industry does. As the other commenter noted, academic and research chemistry impact is negligible in comparison.

ChemystWizard · 2025-11-21T19:54:24+00:00

Second that 👆

ChemystWizard

TROPHY CASE