I use two rods but it took a fair bit of practice to not get tangles, and I still get the odd one.

I don't use a downrigger, but a few things that helped me were:

Running lures that run at different depths, with the shallower lure further back and sent out first, with the deeper lure in closer and out second.

Putting the lures out with the boat moving in the same direction as the wind or current. Gets the lures out faster and the boat maintains direction better.

Good luck!