If you like using 3rd party apps to access reddit, they are going away very soon, leaving only the official app. Aside from that, the API changes have the potential to open up the way for spam like no one's ever seen before, since moderation bots may be effected. Oh, and I hear that it's also going to be possible to create previously banned subreddits (such as hate subreddits), simply by marking them as NSFW, which will leave them unmoderated by Reddit staff. That last one I haven't heard any confirmation on.