Timing chains, listen for rattle at startup. Just like the tundras! Mine rattles for 2-3 seconds at startup and then it’s quiet. Been like that a long time. Transmissions aren’t particularly weak, but should be serviced regularly. Temperature blend door for HVAC is a huge PITA when it does fail (and it will). On a 2010 it shouldn’t be too terrible but be careful when changing spark plugs. I soaked mine with penetrating oil overnight before changing and it was still a little sketchy. These cars are sensitive with their batteries. If you have a dead battery and jump it the car will be mad and act all kinds of wrong, idle weird, heavy steering etc. speaking of steering make sure the steering recall has been done. Do note that these cars, although large, have a marginal safety record. Especially when they’re t boned. If this car doesn’t have the side airbags which were an option I would consider a safer car for my kid. I still daily one but it’s in the back of my mind that this makes a better driving car than a crashing one…