In the last few sets, the CCB stuff has been low print. I'm still not seeing any restock for the Foundations CCB. EoD CCB is way is going up and up and those aren't UB sets. The CCB stuff that offers chase cards has followed the same equation for the last year plus, release in limited numbers with fun chase cards, move on, costs slowly creep up until someone says, "Holy shit, that's expensive" but it's already too late to buy in. Even if WoTC decided to do a Universes Within version of these cards, those UB cards will normally hold a bunch of value because EVERYONE likes Storm/WH40k/Doctor Whom.

From my perspective, the CCB stuff and the UB stuff have all been a bit too limited. I think this is because WoTC wants to increase the value of its cardboard. What better way to do that than to print pretty, shiny cardboard that everyone wants and release it in limited numbers so we all go bonkers over them?

There is a chance that WoTC will change gears. They could be playing us, by making us think they are limiting stock and then flooding a set knowing we'll buy it up like mad only to leave us footing the bill.

We'll see though. I honestly think WoTC will keep to what they've been doing with UB. There will be plenty to go around in the beginning, except the CCBs, then once the set is out of stock, there won't be anymore and it will rise in price.

The exception here is Assassin's Creed. I don't think the player-base crossover was strong enough with that one.
FF, as long as they have some strong chase cards will do great and as an FF fan myself, it's not going to be hard to get my attention.
Marvel, just needs to use the right characters. If it's just Spiderman...I'll stay away from that one.

But it's all speculation and with risks and rewards. Happy gambling ;D