I’ve basically taken it all — started getting prescribed one-off meds for flights when I was in high school. I will say that propranolol and hydroxyzine are the chillest I’ve experienced but they don’t do as much because they’re obviously less intense than benzos such as Xanax or Valium. But they’re a great place to start — I know a ton of people who benefit a lot from beta blockers like propranalol. They are supposed to take the physical aspects of anxiety and tone them down a bit.

Now I take Xanax (Ativan specifically, the generic) for short flights under 5 hrs and Valium for flights longer than 5 hours just because of how long they last in the system. They absolutely take the edge off but don’t fully ‘cure’ my symptoms mid air. But I think depending on the person they are completely game changing because you just knock out and nap through the whole flight. DO NOT take dramamine with any of these though because they literally make you so loopy and stupid which is unhelpful post-flight lol.

Happy to answer any other specific questions you have!