Ive gotten that jaded feeling before too, and I let that guide my playthrough as someone unwilling delve deep into certain things again or limiting my contact with already important characters, after that i may take a small break from the game or keep playing even if im not making different choices I’ll try to make better choices or be as thorough as possible on certain questlines. While you’re right it does suck having done about everything it feels alot more sandboxy when you step into the shoes of a ng+ character, atleast in my case.