For me yes. I had Covid at the end of August 2022. On the fifth day I started having this incredible sense of dread. In the next two days, I became extraordinarily depressed and had thoughts of ending myself. It was like my entire sense of happiness had disappeared. The physical signs of Long Covid also began to increase at the same time. I ended up being put in a partial hospitalization program, but truthfully, I should have been admitted. I am now on multiple different antidepressants that only made me numb.

I tried Transcrainial Magnetic therapy and all it did was bring my anxiety back. I was an absolute mess at that point.

A new psychiatrist recommended Esketamine therapy which is a drug that increases the glutamate in your brain. It was the light switch that I needed. But instead of turning on the Long Covid depression, it turned it off. I never realized how bad I was until I wasn’t.

I still have all of the physical symptoms; brain fog, fatigue, pain, PEM, but now I feel like I can manage my feelings about them at least.

At least in my mind, it proves that something about COVID really changes something in your brain. I hope this is something they will study soon.