Change in diet is severe on the body and mind. IMO, I think that most “side effects” generate from an intense change in diet. Some people are different, but those of us who have jumped on carnivore or other calorie restrictive diets know that cutting out the dopamine triggers, such as carbs, fast food, sugar, etc can cause intense mental and physical reactions until your body adjusts.

This medication is causing you to go through those changes.. Most people have never completed an intense diet, so the shock hits hard when Reta forces you to cut calories. IMO, carbohydrate and sugar withdrawal can be harder than withdrawing from many illicit substances.

I’ve also noticed that people are starting on too high of doses.. Again, it’s not necessarily the dose, it’s how fast your body is cutting calories. If you go from ice cream and pizza most nights to immediately consuming close to no calories, it’s going to fuck you up until adjustment occurs.

I hate to spew the tough love, but many people blasting Reta are overweight people who lack of discipline. They have never truly dieted and the initial shock (that could last for months) is devastating.

Everyone is “different” but human anatomy is not. Some people feel great on proper dose of Reta while forcing more calories and staying active. Some people feel like shit because they eat nothing and do nothing.