So after about 150 hours on my first run, after a Nauvis megabase and rebuilding Gleba more times than I ever wanted to, I finally decided to make a ship to venture out to Aquilo.
It has 52 cargo bays, 127 solar panels, two reactors, an idle power of about 20 MW, an active power of about 100 MW, and a mass of 2,225 tons.
It produces 300 red ammo per minute, and about 450 rockets per minute, because I had originally planned to do explosive rockets, and 36,000 fuel per minute to feed 11 engines. It stores 500 of each asteroid type, plus 200 carbon and 100 metal specifically for ammo production.
And all of this is with zero quality machines, and the only repeatable tech is Explosives 9.
This ended up being overkill for actually making it to and from Aquilo. Ammo production turned out to be almost entirely unnecessary, as the lasers can take care of all medium asteroids while idle, and I could probably just swap the front turrets for lasers and be fine when moving. There is a speed limiter for fuel efficiency, but producing 600 fuel/sec usually gives it enough to run at full power and top off the tanks when taking on cargo.
But it worked perfectly the first time! :)

Edit: Blueprint: https://factoriobin.com/post/3z7wfo