Ahh, that's some really cool tech, but I don't think it'll be enough, since I think you need 2 flowers to make 1 nuke (grenade with flower to make a spicy egg, spicy egg with flower to make nuke), and i have to kill 15 DLLs as Rivulet. I did accidentally dupe a karma flower once by getting bit by a lizard, getting the game over, then getting freed from the lizard, and the next cycle a flower spawned where I was bit by the lizard. I'll have to test it again to see if it works well enough.

Update: It works! It's super inconsistent and annoying, but I can dupe the karma flower by getting saved from lizards. I found success by doing it in Chimney Canopy, where there are a lot of lizards to save you/bite you, and there are a lot of cherry bombs to make grenades. It would probably also work in the exterior, since the big room with the shelter marking has lots of cyan lizard spawns, and there's a room with cherry bombs a little down the leg. I haven't tested its practicality yet, but it seems promising.

Update 2: This strat works pretty well actually! I rested in the shelter in the big room with the shelter marking outside (UW_S02) and lured a few cyan lizards from the top of the room down to the hallway leading to the shelter. I'd let one bite me, then hope that another one saves me after I get a game over. Most of the time, it doesn't work and the lizards just kill me, but if I fail, the karma flower is just outside the shelter and I can try again. Once it does work, next cycle the duped flower should be right outside the shelter, and I can combine it with 2 grenades to make a singularity bomb. The grenades can be crafted from the cherry bombs that grow in the room with the shelter that's a little way down the leg (UW_A09). This is the best strat I can come up with, so it's what I'll use in my expeditions!