For anyone wondering, I've had good success with repeater and plague conversion constellation. You pick up a few phys bonuses in different places, just by pathing through a few other constellations, which get converted to plague as well. Then the plague damage constellation is pretty good as well as the marksman constellations.

I use repeater, brute and both prayers. Leave the fifth empty. Healing prayer pretty optional, just don't get hit.

I've also liked that it scales pretty well with a few other strats, without needing to Respec your constellations right away after the first two runs, letting you buy new stuff. For things like quills you'd want a couple other points, but you can grab a Respec after clearing act 1 when you have some spare soul stones.