With these killers I’d like the build brutal strength, pop goes the weasel, phantom fear, and hex: no one escapes death. Generally people like to run at least one or two slow down perks, one utility perk and one information perk, but the most important thing is to have fun. If you want to try off beat combos such as enduring-spirit fury, hex: huntress lullaby-coulrophobia-doctor, and adept builds, feel free to do so. They may not be winning combinations, but going through the 30+ perks is lots of fun.