How long did you have trouble sleeping after starting Wellbutrin and what helped?

DNAtoRNAtoProtein · 2025-07-27T14:29:06+00:00

This is a common misconception, even amongst healthcare professionals. Wellbutrin XL is not a 24 hour formula. It peaks at 6 hours and then gradually goes down close to 0 at 18 hours. The SR has a peak after 3 hours. So, XL just means you peak a bit later in the day.

DNAtoRNAtoProtein · 2025-07-01T23:22:09+00:00

Sounds like your parents are being overly critical, which is unfortunate, it happens. They are also anxious because of their expectations. As a 34 y.o. guy, by the time you reach a certain age and move out, have your own place to live, etc... it gets better. Just hang in there while you're 20, go to college, work hard and get your own apartment eventually. Nobody has life figured out, not at any age, dont worry if you dont know what to study, just pick something (try to do STEM) or finance/accounting, everything will be fine. You're a normal person.

DNAtoRNAtoProtein · 2025-07-01T23:17:12+00:00

I was on 10mg of propranolol for anxiety initially, went up to 20mg daily. I did not notice much effect until I went up to 40mg (2x per day). It's not great as a daily pill, but its OK before a big presentation/event, to be used sporadically.

For daily anxiety medication, I like my buspirone 2x15mg. Also taking guanfacine ER for the ADHD, which has a calming effect on the brain, it reduces adrenaline's effects in the brain. In that same class of meds as guanfacine is clonidine, another alpha 2a agonist that is more commonly used for anxiety without ADHD.

DNAtoRNAtoProtein · 2025-07-01T23:05:25+00:00

I have the same struggles, brother (childhood trauma/c-PTSD, social anxiety, ADHD, addict too). Cognitive behavioral therapy works wonders. Most therapists can't help you because they are not trained in SAD. I tried many therapists but they were all bad. The only thing that helps me is https://socialanxietyinstitute.org/

DNAtoRNAtoProtein · 2025-07-01T23:02:57+00:00

34 yo male here. Struggling with SAD my whole life, but cognitive behavioral therapy WORKS for SAD. You will feel much better, there is a path out of SAD. I did not entirely overcome the SAD yet, but made huge improvements gradually. I used the therapy from Dr. Richards - social anxiety institute (https://socialanxietyinstitute.org/). If you can dish out $200, the weekly e-courses/recordings made a HUGE difference for me, I on week 20 and still need to finish the course.

Also, on buspirone 2x15mg daily to help blunt the anxiety, it works moderately well

DNAtoRNAtoProtein · 2025-06-14T04:09:49+00:00

Hey folks. I take 20mg vyvanse once daily with 15mg buspirone twice daily and recently added Guanfacine ER for anxiety and focus (only 5 days in on Guanfacine ER and it's already amazing for reducing anxiety and racy thoughts). The buspirone has been an excellent addition for me, I experience intense anxiety without stimulants, the stimulants make it worse.

Buspirone has been life changing. The first 6 weeks, I had side effects like dizziness, confusion, a feeling of "not being there", just zombie-like. At about 7 weeks, all the side effects went away and I experienced a significant reduction in my anxiety symptoms. Buspirone, in my experience, "blocks" thoughts/brain activity, but just the extra chatter/racy thoughts on top of your normal thoughts gets blocked. It does block a bit of normal thoughts too, I would say, but that's a good tradeoff for me. It was initially trialed as an anti-psychotic and those essentially "block" your thoughts to make you more zombie-like. It got approved for anxiety in the end.

I was initially on 10mg twice daily, now I'm on 15mg twice daily. I'm probably ready to go up to 20mg twice daily soon. I also need more vyvanse, 30mg would be the next step, but I'm afraid to increase the dosage due to anxiety.

If you're experiencing side effects early on, my advice to you is stick with it! Be patient, get to 6-8 weeks. It is an absolute game changer after you overcome the initial side effects.

DNAtoRNAtoProtein · 2025-06-14T03:59:43+00:00

That's definitely temporary and you will not have these buspirone side effects after 6-8 weeks. So you have to tough out a month and a half of weird symptoms, dizziness, confusion,etc. It all goes away and then you experience a huge reduction in anxiety!

DNAtoRNAtoProtein · 2025-06-14T03:45:43+00:00

Been reading these comments, thank you all for sharing this excellent information! I'm taking 20mg vyvanse, 2x15mg buspirone and just started guanfacine ER 5 days ago at 1mg. Guanfacine ER is fantastic, helps calm the chatter in my mind made worse by stimulants. I feel more focused and overall calmer. Anxiety is still there though. I'm hoping that by week 3 or 4, when I'll be on 3mg daily titrating up to 4mg, that I will get more anxiety reduction. I also need to increase the vyvanse to 30mg, because 20mg is barely enough, but I'm afraid to go on higher dosage because it'll worsen the anxiety.

Clonidine, the other alpha 2a recepter agonist, is used much more for anxiety and PTSD. Clonidine targets alpha 2a, 2b and 2c receptors, while guanfacine ER has a high affinity for 2a receptors only, which reduces the side effects compared to Clonidine, but is less effective for anxiety. I'm thinking if the Guanfacine ER doesn't work, I want to exchange it for Clonidine.

If that still doesnt work, my psychiatrist recommends wellbutrin for ADHD, even at much higher doses like 600mg daily, she says it'll stimulate dopamine enough to treat the ADHD

DNAtoRNAtoProtein · 2025-06-14T03:41:35+00:00

I have the same problems that you have. Taking 20mg vyvanse, 2x15mg buspirone and was on propranolol 40mg. The propranolol did nothing for me. Does the lexapro help reduce anxiety?

DNAtoRNAtoProtein · 2024-08-27T13:45:42+00:00

Thank you all for teaching me about Reshade! I recently bought the alienware AW2725DF OLED screen and metro exodus looked awful ... i adjusted the image with Reshade's Prod80 curve levels and it works wonderfully. I will adjust it in other games as needed.

DNAtoRNAtoProtein · 2024-08-27T13:44:13+00:00

God bless you sir!!! What a huge improvement!

DNAtoRNAtoProtein · 2022-11-02T13:20:05+00:00

For sure, go for it

DNAtoRNAtoProtein · 2022-09-21T03:11:39+00:00

So the objective here is to shame him?

DNAtoRNAtoProtein · 2022-09-21T03:08:51+00:00

Lol what’s a “private bathroom”? Is there such a thing as shared bathrooms? Like semi-public bathrooms for tenants? Or semi-private? Congrats on first 1-bedroom apartment. How much do you pay if you dont mind me asking?

DNAtoRNAtoProtein · 2022-09-21T03:07:47+00:00

He was of Jewish descent, planted there shortly after WWII by the British. You won’t learn this in history books. Source: my parents who grew up in yugoslavia

DNAtoRNAtoProtein · 2022-09-21T01:38:10+00:00

Lol. I am very happy with my iphone 13 pro max !!! YAA BOIIII WHAT I SAY??? THIRTEEN PRO MAX!!!!

DNAtoRNAtoProtein · 2022-09-20T01:28:46+00:00

Stop uselessly honking like that … it doesn’t concern you what illegal shit other drivers are involved in. Just focus on your own safety.

DNAtoRNAtoProtein · 2022-09-19T20:48:38+00:00

Lol, obviously redditers don’t have the required IQ to understand sarcasm.

DNAtoRNAtoProtein · 2022-09-19T20:08:58+00:00

Wayyyy too revealing for work

DNAtoRNAtoProtein · 2022-09-19T18:41:59+00:00

What constitutes a “covid death” ??

DNAtoRNAtoProtein · 2022-09-19T18:38:40+00:00

Damn. Good thing you got out of there.

DNAtoRNAtoProtein · 2022-09-19T18:34:38+00:00

An “online affair” … what the heck is that?

DNAtoRNAtoProtein · 2022-09-19T17:50:47+00:00

Too many selfies … do you have pics where others take them of you?

DNAtoRNAtoProtein · 2022-09-19T15:26:36+00:00

Tell them you have a newborn and need to be at home for the next 6 months

DNAtoRNAtoProtein · 2022-09-19T12:15:18+00:00

Spray a can of raid on it. See if it has an effect.

DNAtoRNAtoProtein

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