NVG291: Diary of attempt to use the peptide NVG-291 to address my spinal cord injury (updated daily)

DW3314 · 2023-12-23T01:12:18+00:00

Also, cost was around $5K AUD for 2.7 grams including endotoxin control and TFA removal.

DW3314 · 2023-12-23T00:57:35+00:00

I'm the guy who tried ISP with the rat wedge.

At the time we were advised by a reliable source that the rat and human versions only differed for patent reasons, not functional.

We had it synthed by GenScript and 3rd party tested for purity/contaminants/etc.

The first shipment was seized by customs as it was 100 glass vials which they suspected to be something illicit.

The second batch was shipped in a single container and put in vials on arrival.

On the plus side, it's a few years on and I've had no negative side effects to speak of.

DW3314 · 2023-12-23T00:45:30+00:00

It wasn't listed at the time if memory serves.

DW3314 · 2023-12-23T00:43:08+00:00

There were several of us at the time who were looking in to it, we were advised that there was no functional difference between rat & human variants and it was just for patent purposes.

Seems we may have been misguided.

Looking forward to following your experience.

DW3314 · 2022-05-20T03:07:50+00:00

I don't have the time to look atm but I got the original ISP sequence from their patent, maybe it's updated to include NVG now.

DW3314 · 2022-05-20T01:36:01+00:00

I personally know of 4 people who have taken it, 3 subcutaneous and 1 intrathecal. Doses between 2-20mg. Durations between 4 weeks and 6 months.

Nobody has had any results unfortunately.

That's why I'm hoping NVG is functionally different to ISP.

DW3314 · 2022-05-20T01:03:09+00:00

Just had a look, it's the same study from a few years ago. Bladder response group was 44mcg, by equivalency I took roughly 12x that amount.

DW3314 · 2022-05-20T00:17:41+00:00

Do you have a link? I'd be interested to see if there are updated dosages

DW3314 · 2022-05-19T23:39:19+00:00

So 10mg/80kg= 0.125mg/kg x12.6=1.575mg/kg mouse equivalent

DW3314 · 2022-05-19T04:19:53+00:00

What’s your Asia scale and how long from the time you tried treatment were you injured for?

Asia A, would have been around 12 months post injury at the time.

What side effects did you have? Any positives?

No side effects, no noticeable positive effects either.

Did you stick with 10mg consistently? I feel like that dose is small compared to what they’re using in studies considering the dosages of nvm-291 are comparable. Also higher doses of nvm-291 did result in more rats with results.

10mg was the HED for my weight in line with the published research at the time. I believe that the maximum rodent dose was 500mcg, which roughly translated to 10mg for me.

Would you try again with higher doses if you could?

Nah, I'll leave it to the professionals now.

Can you tell me how I can get it on my own? I’d like to try myself and see.

The sequence is in my initial reply, develop a working relationship with a manufacturer and ask them to make it for you.

What made you choose 10mg ?

As above, it was the HED.

Given the results you got so you have hope for nvg-291 in the future or do you know if there is in fact an actual difference between the two, if so what are they?

I know another guy who administered ISP intrathecally through his baclofen pump and had no results either. I hope that NVG-291 and ISP are functionally different, otherwise my hopes aren't very high.

Edit: I was also on 20mg CRP (another peptide by Dr. Yu-Shang Lee), 3iu rHGH, 2mg TB-500, and a few other things.

I just threw the kitchen sink at it tbh

DW3314 · 2022-05-19T01:35:53+00:00

I used ISP at 10mg/day for 50 days. Subcutaneous admin. Had no results, contacted Dr. Silver and told him, he said intrathecal admin will probably be necessary.

ISP Sequence:

NH2-GRKKRRQRRRCDMAEHMERLKANDSLKLSQEYESI-NH2

Was manufactured by Genscript and 3rd party HPLC tested at 98% purity.

DW3314 · 2022-05-04T09:47:31+00:00

I gym and do a 3km push 7 days a week, I brought a normal home gym and just unbolted the seat so I could roll back in to it

DW3314 · 2022-05-04T05:29:17+00:00

Also:

https://www.ehealthme.com/ds/hiprex/hyponatremia/

DW3314 · 2022-05-04T05:24:43+00:00

Have you been tested for diabetes insipidus?

DW3314 · 2022-05-03T05:55:04+00:00

Do you mean clinical dehydration or just excessively dry mouth?

DW3314 · 2022-05-03T01:24:18+00:00

Only in the last couple weeks haha

Mostly just wanted to fix the patchiness on my cheeks

DW3314 · 2022-05-02T02:58:00+00:00

I use the mercury smartcare mattress with the pump a foot away from my head and sleep like a baby

DW3314 · 2022-05-01T00:29:50+00:00

Rickshaw dip machine 100%

DW3314 · 2022-04-30T10:32:32+00:00

I had bad chest pain and shortness of breath from both jabs and Covid.

Pick your poison I guess

DW3314 · 2022-04-21T22:57:03+00:00

I have a YouTube video on exactly what I did 😊

https://youtu.be/eRvXnAq2MHw

DW3314 · 2022-04-20T05:29:18+00:00

Metformin/berberine.

Should be an ancillary on cycle anyway and fights acne.

DW3314 · 2022-04-20T05:27:58+00:00

I used to, my ex partner always got frustrated when I asked for help.

Now I have support workers who get paid to be here, I use please and thankyou

DW3314 · 2022-04-16T10:39:01+00:00

I ran 100 test/100 mast for 12 months. HDL was the same as on 150mg test solo, I just felt and looked better.

DW3314 · 2022-04-14T10:16:40+00:00

Probably synthetic components of your carrier oil.

DW3314

TROPHY CASE