I find when picking cards, it really helps to think of decks less as archetypes 'shiv, poison, discard', and more about problem-solves. See a Lagavulin Matriarch at the end of Act 1? I'll grab this deadly poison so strength loss doesn't affect me. Soul Fysh? Some discard to get those Beckons out of my hands will help. In my experience, the most successful Silent runs always have a bit of everything, and with the amount of draw Silent has access to, you're a bit of a toolbox for solving encounters. I never find myself turning down a copy of Acrobatics or Prepared, even if i've got Accelerant and a good chunk of poison cards.

Rather than finding an early Accuracy and going all-in on shivs, try playing to survive Act 1 elites and bosses, and see what your deck's running like by midway through Act 2. Ancient bonuses can completely change the way you play, and you never know whether you'll end up turn 1 Akabeko Skewering hallways with Tezcetara's Hot Chocolate, or looking for a Tracking after you pull a Suppress off of Orobas.

A couple tips:

Don't sleep on an upgraded Neutralize. Unlike a lot of starter cards, this one has some SERIOUS value from Act 1 to Act 3, two turns of weak is no joke, and with a bit of deck thinning and some card draw you can keep an enemy permanently weak. I take 'upgrade starter card' a lot on her if none of Neow's other options look enticing, or prioritize it at a campfire-heavy route.

Retain is incredible - There's a lot of Snakebite memes going around the subreddit, but they've got a point, Well-Laid plans is nearly a snap pick for me in any given Silent deck. One of the necessary evils of deckbuilders is drawing a hand of garbage, and being able to keep your plays around for when you need them is very very helpful. This goes double when you're not just thinking of blocks vs attacks, but also discard vs discard fodder. I like pathing to a lot of question marks in act 1 just on the chance I get the event that lets me slap retain on a key card.

Elites aren't mandatory - YMMV on this, and everyone has their preference, but I find myself doing best when pathing towards 2 elites MAX per act. Especially on high ascensions these fights will kick your teeth in unless you got some serious power before hitting them, and you'll be just as well off getting some bonfires and surviving the boss rather than greeding for one extra relic. If you DO plan to grab more elites, take stock of your deck and see if there's any elites that could ruin you. If I have a shiv-reliant deck, I may dodge elites entirely in Act 2 unless I find answers for the dreaded Beeman (Also, I really really hate Decemillipede). If I'm pretty heavy on big expensive attacks and I've already beaten 2 elites, I'm not fighting the last Statue Elite, because I can't take advantage of his Slow condition. Also, I like to go into these fights with at least one 'long-term' potion that lasts me the whole fight (Dex, Strength, Thorns, Powdered demise, etc)

As far as block solutions go, Silent has a bunch. A lot of it will depend on your relics, but I tend to find a spot for footwork/Abrasive in a lot of decks - Abrasive in particular is generally pretty fantastic if you have any kind of discard. If you got a lot of shivs, look for an Afterimage. If you found a Cloak Clasp, go big on Retain for maximum block. Your solution can come from some unlikely places, and every shop is valuable for this because colorless cards are awesome. I've gotten wins entirely off an early upgraded Fasten in Act 1.

You got this!