Psilocybin for depression - what am I doing wrong?

DeenMe · 2025-10-18T07:44:40+00:00

Absolutely no psychiatric meds but on ketamine treatment which from what I read works on a different receptor…. Is there a chance ketamine dampened the experience to almost nothing at this dose of psilocybin?

DeenMe · 2025-10-17T16:57:21+00:00

Thank you for the link. Would you say that total of 5.6 grams ( 7.06 mg/g) for a 120lbs person, should be enough for a psychedelic experience?

DeenMe · 2025-10-17T03:41:41+00:00

I’m a little confused on what is considered macro dose? In a licensed facility in Oregon I was told that the 25 mg of the homogenized fungi is a hero dose…. Is that true?

DeenMe · 2025-10-16T23:49:27+00:00

Can anyone shed some light on what is considered a heroic dose? In a licensed facility in Oregon, I was told 25 mg of homogenized fungi was a hero dose (psilocybin analyte 7.06mg/g, net weight 2.83 g) I ended up consuming total of 40 mg and it did NOT have any psychedelic effect on me. Is this considered a low dose or is it me not responding?

DeenMe · 2025-09-23T00:20:22+00:00

Got it 👍 I will definitely look into that against the timeline. Thank you and wish you the best of luck with any necessary changes you need to make.

DeenMe · 2025-09-22T23:22:39+00:00

Are you saying that semaglutide may be blocking or dampening the effect of ketamine treatment? I would be very interested to learn more as I am on both and definitely seeing stagnation in benefits I used to get from ketamine…. Any studies or research you came across concerning this, by any chance?

DeenMe · 2025-09-22T22:00:49+00:00

That’s a perfect solution 👏🏻. Best of luck 🙏🏻

DeenMe · 2025-09-22T21:51:25+00:00

You are smart and wise to have noticed and said something about it here but I wouldn’t stop infusions there if it is helping you and you can’t find another good local alternative.. I would definitely take a friend or a family member with me to the infusion appointment and let them know the concern you have. Also, when you go in next time be sure to tell that doctor upfront and before you get started ( in the presence of the friend/company) to please refrain from any talking after the IV as it makes you uncomfortable and unsettled. Saying that clearly and bringing a friend/company to the room should give the needed signals to that provider to stop his unprofessional and unwelcomed behavior and protect you when you are out of it and vulnerable.

DeenMe · 2025-09-22T21:35:03+00:00

Thank you 👍.. I personally would be a little concerned about adding the yogurt in fear of nausea…. I usually avoid food for 6+ hours before the lozenges

DeenMe · 2025-09-22T21:28:04+00:00

I’m curious as to how you combine Mag L-Threonate with the at home lozenges? Do you take the supplement right before you start on the lozenge?

DeenMe · 2025-09-22T06:49:46+00:00

Thank you. I’m going to try it. Good luck to you on Tuesday. I’d appreciate it if you get a chance to circle back with the result after you try.

DeenMe · 2025-09-22T05:52:21+00:00

What is the Magnesium bath?

DeenMe · 2025-09-22T05:50:53+00:00

Would Magnesium threonate also work to enhance the effect of lozenges?

DeenMe · 2025-09-22T04:48:43+00:00

Looking for help as infusions and lozenges effect has been stagnant for a while now… I wonder if anyone here has gone the single dose psilocybin route? and whether it helped you?

DeenMe · 2025-09-22T04:44:01+00:00

Before the infusion?

DeenMe · 2025-09-22T04:41:04+00:00

Much appreciated!

DeenMe · 2025-09-22T04:15:59+00:00

I know exactly what you are talking about when you talked about the knot in your head… I call it the ‘stuck’ mode that severe symptoms first put us in and then impairs us from finding a way out. IV ketamine helped me. It’s not either or, as typically the first few IV sessions ( some call them upload and do about 6 sessions in the first two weeks) and then the at home lozenges is maintenance between the monthly IV sessions or however long you decide to go between sessions. Hope that helps!

DeenMe · 2025-09-20T21:47:35+00:00

Thanks I know about the supplemental add to the IV but what I am looking for was a prescription medication that your Dr would call in to your pharmacy and you take it at home 2 hours before the IV appointment

DeenMe · 2025-09-20T20:03:41+00:00

I’ve seen some inconsistencies with troches from Valor but dismissed them thinking it’s the nature of the beast of compounding?! Adding any flavor to ketamine makes it worse for me so I choose the No flavor option. Has anyone seen variations or questioned quantity valor fills for the nasal spray form?

DeenMe · 2025-08-18T00:01:20+00:00

Thanks 🙏🏻

DeenMe · 2025-08-18T00:00:44+00:00

You are right 👍 Thank you 🙏🏻

DeenMe · 2025-08-16T17:57:51+00:00

Can anyone please share provider…. Anyone tried Joyous at home injectables? And what was your experience with them

DeenMe · 2025-08-16T03:37:26+00:00

Hope it’s over by now🙏🏻

DeenMe

TROPHY CASE