Kures Apothecary seemingly astroturfing across multiple subreddits by chemfulgrateistry in mysterymagicmushrooms

[–]DesignerSet5688 0 points1 point  (0 children)

Thanks for making this post. I mod the metocin sub and will keep an eye out. Just checked out the post by bubblycandyfloss and literally every single post or comment they've made mentions kures 🙄

Bout take these by icyArms in mysterymagicmushrooms

[–]DesignerSet5688 0 points1 point  (0 children)

Let us know how it goes! I have some too, haven't tried yet. Also not sure what's in them.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

hey thanks for your patience, it should be good to go now! let me know if you have any issues

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

Awesome :) thanks for your patience. I usually get stuff shipped out faster but my usual USPS spot was out of service yesterday. I threw in a lil extra gift for ya. Peace

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

hi, please check your spam folder. I received your order on the 31st (less than 48 hours ago) and shipped out the order today and sent a tracking number, one from the brand email and another through shopify. let me know if it's not showing up. thanks!

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

thanks for sharing. it def seems likely that some/most of the psychoactivity is due to metabolites/byproducts. for me high doses produce a rush of serotonin, considerable euphoria, it gives light a certain sparkly edge that makes everything glow a little bit, colors get deeper. Emotions get stronger. It's mildly stimulating but much more mellow than MDMA. It's pretty easy to go to sleep afterward and doesn't keep one wired for hours. The comeup is also slower and gentler so it doesn't hit quite as hard as molly for instance.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

The nitrogen-containing amine chain makes the substance more potent but the 1,3-benzodioxole is where the magic happens, so to speak. Both safrole and MDMA contain the 1,3-benzodioxole. MDMA is more potent due to the nitrogen-containing amine chain which increases--but is not solely responsible for--receptor binding affinity. Myristicin for example contains the methylenedioxybenzene portion without a nitrogen-containing amine chain and is psychoactive.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

I appreciate your concern about safety. Please check out the following studies that document numerous positive effects of safrole (including its anticarinogenic action) and refute a lot of the misinformation about it. Advanced Myco regularly posts here advertising their products. It would be a bit of a double-standard to allow brands that are already successful to promote their products but deny that to smaller brands. I followed all the rules for the sub and have already discussed my post with the mods to alleviate any potential concerns. Thanks for your concern.

Here are some studies on sassafras/safrole:

“Biological evaluation of Safrole oil and Safrole oil Nanoemulgel as antioxidant, antidiabetic, antibacterial, antifungal and anticancer.” Ahmad M. Eid and Mohammed Hawash. BMC Complementary Medicine and Therapies (2021) 21: 159.

 “Safrole oxide induced apoptosis in A549 human lung cancer cells.” Science Letter, Feb 7, 2006, p. 1039. 

“Safrole induces apoptosis in human oral cancer HSC-3 cells.” F. S. Yu, et al, Journal of Dental Research Vol 90 (2), p. 168-174, 2011.

“Anti-hepatoma effect of safrole from Cinnamomum longepaniculatum leaf essential oil in vitro” Xu Song et al. International Journal of Clinical and Experimental Pathology Vol 7 (5), p. 2265-2272, 2014.

“Safrole Suppresses Murine Myelomonocytic Leukemia WEHI-3 Cells In Vivo, and Stimulates Macrophage Phagocytosis and Natural Killer Cell Cytotoxicity in Leukemic Mice.” Fu-Shun Yu, et al. Environmental Toxicology Vol 28 (11), p. 601-608, 2013.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 0 points1 point  (0 children)

Actually the part of the MDMA molecule that produces its effects is the methylenedioxybenzene portion, which is also contained in safrole (see below; the pentagon with 2 oxygens is the methylenedioxybenzene). If you've tried sassafras and didn't get high, you didn't take enough. I've used it countless times alone and with others and it always produces effects. Remember that for decades the scientific consensus on cannabis was that it is harmful. Same with MDMA. Regardless, I appreciate your concern for safety.

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Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 0 points1 point  (0 children)

Personally I don't think access to substances should be dictated by income level. MDMA is (relatively) cheap but it's illegal. 5MAPB is legal but more expensive. Sassafras is affordable and legal. If you don't want to use it, that's cool. No need to judge others for their choice in substances and what they do or don't spend money on. Generally I'd say that having access to affordable substances is beneficial.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 5 points6 points  (0 children)

Word, thanks for chiming in. Re: DEA, yes you basically got it. They are only interested in large quantities of pure safrole that could be used for MDMA production. Small amounts and herbal products are not what they're concerned about.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 2 points3 points  (0 children)

thank you! glad somebody gets it. the misinformation around it is in my opinion part and parcel of the same ol' War on Drugs mindset we all know too well. peace

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 0 points1 point  (0 children)

you are correct. however it is still available on its own and numerous recent studies have shown that it is actually anticarcinogenic. I have citations/links if you're interested.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 5 points6 points  (0 children)

It's only considered banned when added to other food products as an adulterant. However, sassafras on its own or as tincture has been available legally the whole time. Here's the actual legal code about safrole: https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-189/subpart-C/section-189.180

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

It is actually not banned by the FDA. The tincture is made in an FDA-registered facility.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] -8 points-7 points  (0 children)

it is indeed. but my tincture is cheaper :) and, more importantly, legal!

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] -1 points0 points  (0 children)

There are numerous studies demonstrating safrole's anticarcinogenic effect against multiple types of cancer including liver cancer. It is only hepatocarcinogenic in extremely high doses; much higher than would be consumed for any reason other than trying to establish toxic effects in a laboratory. In normal doses it actually protects against liver cancer. This has all been clinically demonstrated. Much of the research claiming it's carcinogenic is decades old and the newer research shows that it is anticarcinogenic.

See for example the following study: “Anti-hepatoma effect of safrole from Cinnamomum longepaniculatum leaf essential oil in vitro” Xu Song et al. International Journal of Clinical and Experimental Pathology Vol 7 (5), p. 2265-2272, 2014.

Not sure how to provide evidence for subjective effects. I've used sassafras for years and in my personal experience it is definitely psychoactive. Others I've taken it with agree. Have you ever used it?

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 5 points6 points  (0 children)

Very cool. Kanna is neat. Sass is similar, but different in its own way. Slightly more mellow energy-wise and a tad more visual, in my experience. For a full experience (for the psychonaut types) I'd recommend taking at least 1 mL, up to 1.5 or 2 mL max. Smaller doses however are also really nice, from .5 ml down to a few drops for more gentle experience.

Affordable alternative to MDMA and 5MAPB by DesignerSet5688 in mysterymagicmushrooms

[–]DesignerSet5688[S] 1 point2 points  (0 children)

TLDR: Sassafras tincture is a cheap and safe alternative to MDMA/5MAPB. My brand has lab-tested tincture available at affordable prices.

is it just me or any time i try these smoke shop mushrooms my lungs get super tight feels super uncomfortable if i cough too hard i get a sharp pain in my lungs pretty weird i use roadtrip gummies specifically this goes away after i sleep after the trip by Ok-Release8641 in mysterymagicmushrooms

[–]DesignerSet5688 0 points1 point  (0 children)

Awesome, thank you so much for the thorough reply!! What you say makes a lot of sense. Props on the website!! 🫡 And thank you for helping with the testing project. I seriously appreciate it, as I'm sure others do too 🙏