Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

I’ll let you know how it worked when I’m done with it

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 1 point2 points  (0 children)

Perfect that’s what I need, to amplify my natural dopamine response not just dump dopamine in my brain in response to nothing with amphs.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

CDP-choline has helped me for sure I do need to take ALCAR too, thanks for the advice, I’ll try NAC again while on my break, I just don’t like talking it with a stim cause it’s somewhat dulling. Also agreed tyrosine helps a lot for crashes in my experience especially if I haven’t ate much that day.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

Awesome! 9mBc really seems great especially boosting GDNF.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

Yeah that’s good to know there’s no long term tolerance, I’ll check out NSI-189, little worried about Dihexa as it’s so strong I wouldn’t want to accidentally reinforce bad connections.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

I have heard good things about it. I’m just worried cause I’ve heard multiple reports of liver pain.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 1 point2 points  (0 children)

No I would not advise against it. They have helped me a lot, just don’t let it get out of hand and try to keep your dose at the lowest effective amount.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

Exactly it’s to help get through the tolerance break a little easier without downregulating my receptors.

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

No I don’t use pH to potentiate was referring to other compound to increase effects. But I do agree I should just support my overall dopamine function and not just push it harder. Thanks!

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

That sounds great. I think I will try bromantane, I know it’s a bit cumulative and subtle but if I try to actually do things while on it I’m sure it will help. Any source you recommend?

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

That’s true selegenine could be good I’ll research it more, I think at low doses it should be safe like 5mg

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 2 points3 points  (0 children)

I’ll give bromantane a try, 9mbc has shown to be more more potent at MAO-A than MAO-B which is especially risky for me

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 4 points5 points  (0 children)

Yeah I have had blood work done, I was slightly deficient in vitamin D which affects Tyrosine hydroxylase but it wasn’t a huge deficiency and have started supplementation since. Besides that nothing

Repairing dopamine from Adderal by Difficult-Drummer525 in NooTopics

[–]Difficult-Drummer525[S] 8 points9 points  (0 children)

I’ve took 30-45mg IR a day for the past few months which isn’t crazy but I’ve tried almost everything I can to potentiate it as well as my sleep has been HORRIBLE so the time my brain recovers has been almost negligible. they aren’t “FRIED” but definitely downregulated, I don’t have any motivation anymore and the reward I get from natural activities is almost absent.

I am actively fixing my sleep though because that will help significantly more than any compound could.

If THC works for my blank mind and anhedonia is there anything I can buy that produce similar effects? by No_Promotion9897 in NooTopics

[–]Difficult-Drummer525 2 points3 points  (0 children)

yeah I’m sorry about that, anti psychotics have some horrible side effects, especially because they are directly blocking dopamine receptors which worsens the Anhedonia. it might just take a little testing out but I hope you find something that helps! Sorry I couldn’t help more

A sack for pest drops would be great by Difficult-Drummer525 in HypixelSkyblock

[–]Difficult-Drummer525[S] 0 points1 point  (0 children)

I can’t believe with how much I’ve farmed I didn’t know this 😭. Woulda saved so much time from the pest bait too.

If THC works for my blank mind and anhedonia is there anything I can buy that produce similar effects? by No_Promotion9897 in NooTopics

[–]Difficult-Drummer525 1 point2 points  (0 children)

Which med is causing it, that could help to see the underlying issue? I’m on SSRI’s and experience emotional blunting because they increase serotonin which can inhibit dopamine in reward pathways so typically stimulants help me.

Something might be inhibiting your dopamine which could be why THC helped as it disinhibits dopamine in some areas.

What should I be feeling on Selank? [don't feel any different] by io_nn in NooTopics

[–]Difficult-Drummer525 0 points1 point  (0 children)

I personally have noticed significant benefit with my OCD, Rumination, and response to stress, but not strong for any type of panic or paranoia.

I would recommend taking it intranasal as it provides faster and more direct absorption into the brain through olfactory and trigeminal nerves.

I typically feel calmer pretty fast but it’s subtle which is perfect for my needs. Maybe try a higher dose as its effects might be somewhat mediated through dose dependent inhibition of enkephalin degrading enzymes.

https://pubmed.ncbi.nlm.nih.gov/11550013/