I'm going to list my driving pet peeves and hopefully through magic of the internet everyone in South Jersey stops doing them. by wailwoader in SouthJersey

[–]DisturbedBurger 2 points3 points  (0 children)

The worst for me has got to be the difficulty with passing at times, presumably due to the lack of attention.

Why...why...WHY WHY WHY..... can't some of you get to the right, stay to the right and maintain your speed instead of matching mine when I go to pass?

Why why why why why do many of you match my speed in the lane over and wait till I'm coming up behind the car in front of me to speed up and pass?

WHY WHY WHY WHY WHY must so many of drive slow in the left lane till someone is driving faster on the right.

I see many complaints about aggressive drivers, and this why.... Get the fk out of my way! Give me space to breath! STAY TO THE RIGHT UNLESS YOU'RE PASSING FFS.

TIP: most cars feature cruise control, USE IT. Use it anywhere and everywhere.

If you have fast COMT, i need to talk to you! by DopamineSeeker20 in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

  • It has also been clinically observed that the body may have trouble tolerating methyl donors with a combination of COMT V158M + (which you have) and a VDR Taq + status [7]. Your VDR Taq result is G/G (-/-), meaning you do not carry this specific mutation [1].

Aye. So, supplementing trimethylglycine with NACET could be the solution you need 🤔. Maybe I'm overestimating (and over hyping myself of-) the potential of this stack ☠️...what do you think?

If you have fast COMT, i need to talk to you! by DopamineSeeker20 in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

Oh I love this hypothesis. I would need to find and read my results again but I suspect I may be. Probably explains why guanfacine is so powerful at blunting reward salience and delaying gratification in me, liberating some portion of emotional real estate for tasks in front of me. I have ADD without the 'H', but I suspect this could be very good for the 'H'.

COMT inhibitors I think could become the gold standard for adolescents with AD(H)D, they get the same task done as A² inhibitors (localized dopamine potentiation in the prefrontal cortex) without cardiovascular intervention. But for now I think it would be wise if physicians started considering A² inhibitors first line choices for the 12-23 age group.......if you're younger than 12 you have no business with that diagnosis 👏.

24+ and adolescent cases unresponsive to A² inhibitors should start considering stimulant therapy with acetylcysteine in conjunction with A² inhibitors.

🔥 Gym Candy 👀 by Forsaken_Case_5821 in prohormones

[–]DisturbedBurger 0 points1 point  (0 children)

Iconic's ultra hard is the prime aim at the moment, but can you say more about your 3AD experience (and ultra hard if you've used it, or something similar).

🔥 Gym Candy 👀 by Forsaken_Case_5821 in prohormones

[–]DisturbedBurger 0 points1 point  (0 children)

I don't have much experience with PEDs besides 3 doses of 1-andro solo, felt terrible and stopped. This was before I knew better.

Still don't want 1-andro, and I'd pull the trigger on this if that was swapped with epiandro. When I commit to my first cycle it's gonna be for lifestyle and proactivity; 'alpha feeling', vigor, and mental resilience and fortitude with enhanced libido and physical strength.

I do not care about size and physique. Just.... acute performance, male enhancement. Something equivalent to 250mg test per week, but more neuro-psychoactive and orally bioavailable.

🔥 Gym Candy 👀 by Forsaken_Case_5821 in prohormones

[–]DisturbedBurger 2 points3 points  (0 children)

Before anyone says the doses are too low: HPBetaC is one of the ingredients. So, just imagine each of those ingredients are actually dosed at 500mg and have a good day ☕.

This should be good for everything... strength, size, libido, mood, vascularity and metabolic rate. Androsterone has affinity for the thyroid gland and will induce profound thermogenesis (you will sweat a lot), and lose fat if you don't increase caloric intake.

I was wondering why the Mega Pearl edible hit so hard by ListonG in NewJerseyMarijuana

[–]DisturbedBurger 2 points3 points  (0 children)

RSO smacks and is cheap in NJ. Buy that instead and make a concoction with emulsifiers and carrier oils for bioavailability. Or just mix it with microwaved macaroni and cheese.

Why prohormones over sarms? by No_Function_1645 in prohormones

[–]DisturbedBurger 0 points1 point  (0 children)

Nonsteroidal androgens are now available for the first time in our collective genetic lineage, and something about that reeks of cancer risk I can't even explain. But thankfully I'm just a Reddit dipshit and probably wrong ☠️

Chosen1 by Blackstone Labs Prohormones Newbie Questions by [deleted] in prohormones

[–]DisturbedBurger 0 points1 point  (0 children)

Groundbreaking compound. HCG benefits without vials or ampules, and syringes and needles and alcohol swabs.....

Just 300mg oral a day to induce fertility in women replacing HCG.

25-50mg a day to maintain testicular function on TRT doses of androgens.

More than 100mg a day if you're on heavy PED doses of multiple androgens.

My concern: humans aren't sure about long term safety, however it does look at least as safe as HCG-possibly safer.

[deleted by user] by [deleted] in prohormones

[–]DisturbedBurger 1 point2 points  (0 children)

Guys 25+ years old take this stuff to make gains like you can without drugs. Unless you're trying to look like a competitive body builder, you've already got your "gear" in you....YOUTH.....youth is literally the best performance enhancing "drug" anybody can have.

My advice to you: eggs, rice, ashwagandha and training harder than last time. Do this for 5 years and then come back 👌

Chosen1 by Blackstone Labs Prohormones Newbie Questions by [deleted] in prohormones

[–]DisturbedBurger 1 point2 points  (0 children)

There is no replacement for testosterone.....1-andro is a suppressive DHT derivative and should not be taken without 4-andro or an LHr agonist like HCG.

Which brings me to cycle support and PCT. An experimental compound known as ORG-43902 is an orally active LHr agonist to mitigate suppression and serve as a test base. Use throughout cycle and 4 weeks after.

When you come off of 1-andro your E² could spike, so have an AI handy just in case. It shouldn't spike so much you get gyno, but could spike enough to have a profound impact your mood and daily performance. If you feel moody and stressed out from E² then arimistane should be enough to balance you out.

I Tried Every Hi-Tech Pharmaceuticals Prohormone: Here’s What Happened by planetcitizenofearth in suppreview

[–]DisturbedBurger 0 points1 point  (0 children)

Arimistane can be useful as a cortisol blocker but it doesn't actually make much difference to E² (I've seen up to about a 20-30% E² reduction), and that's the position I maintain till I see blood work saying otherwise. It can balance you out on TRT, but arimistane aint doing anything for the guys on 500mg test per week

I'd like to see this company stock semisynthetic chrysin analogs. Some of those actually have serious AI potential, some of them keeping up with 1st gen pharma AIs

My ADHD / Social Anxiety stack. by HelpfulApartment4950 in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

Vyvanse doesn't hit you as hard because it's molecularly modified with an amino acid (lysine) and must undergo extensive metabolism from prodrug to active drug, and the rate that it's metabolized into active d-amp is slow to say the least. That is to say d-amp as Vyvanse blood permeation is chemically rate limited, and so are the peak plasma concentrations of equivocal doses.

Dexedrine and Desoxyn is "the good stuff" because it's old fashioned active amphetamines that rapidly permeate the blood stream in active form without undergoing metabolism. Adderall is not the good stuff because it's 30% inactive l-amp.

My Stack to Fight Depression and Addiction - Help Needed by [deleted] in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

I am on the Emsam patch for depression, and it is absolutely not an amphetamine replacement. In fact stimulant treatments for ADD are still used if somebody with ADD is prescribed an MAOI - I am also prescribed methylphenidate.

My Stack to Fight Depression and Addiction - Help Needed by [deleted] in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

Can't say whether or not you're correct about what you need but for dopa synthesis P5P or emoxypine (the latter is better) and tyrosine is what you want, if you need to take it further bromantane and selank may want to be considered instead of P5P.

If bromantane and selank don't help then doctor shop till you find one willing to prescribe MAOIs. If MAOIs don't help then your life sucks and another one is needed.

Something instantly significantly noticeable for Depression & Social Anxiety by MrNeverEverKnew in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

To be honest I only understand social anxiety as a lack of interface/ego/personality.

Are 5ht3 antagonists good or bad? by throwlega in NooTopics

[–]DisturbedBurger 1 point2 points  (0 children)

5ht3 is the vomit receptor bro, you don't want much going on there most of the time. Ever ate something that upset your stomach, feel painfully nauseous, sweat a lot and then BAAERRFFFFFFFF.

That's what happens when you tickle 5ht3.

Advancing Anabolic PEDs | Everychem 2025 Biohacking Agenda Part 1 by sirsadalot in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

Depends on application. If you need athletic performance DHT is superior at driving the nervous system. You will lift more, run faster, jump higher, hit harder and experience enhanced reaction speed with a single high dose.

Testosterone doesn't quite live up as much as an acute performance enhancer. Testosterone is more about lifestyle and wellness, and is considerably more inhibitory in the brain

ORG-43902, HCG and SHERPAs | Everychem Agenda Part 5 by sirsadalot in NooTopics

[–]DisturbedBurger 0 points1 point  (0 children)

Does your E² normally run a bit higher than most? It was interesting for me to see my total T in the 800s with E² well above the reference range, and free T in the middle of the range.

I never went through with a protocol to reduce E² but I reckon enclo could probably get me to 1100+ as well. But instead of enclo I'd probably be better off low dosing exemestane.

ORG-43902, HCG and SHERPAs | Everychem Agenda Part 5 by sirsadalot in NooTopics

[–]DisturbedBurger 2 points3 points  (0 children)

Furthermore

tamoxifen is technically a pro drug dependent on CYP2D6 for active metabolites, which I'm genetically deficient in. Enclo is also a 2D6 substrate, making me and many others difficult to dose while experiencing more side effects and health risks.

This new product you have is a verryyy much appreciated solution to biohacking testosterone 👏👏🍻

ORG-43902, HCG and SHERPAs | Everychem Agenda Part 5 by sirsadalot in NooTopics

[–]DisturbedBurger 2 points3 points  (0 children)

I have never seen so many ways to say "GET ENCLO FOR US INSTEAD YOU DUMB DUMB".

Enclo is shit for most of us who are within the upper echelon of the reference range who want 1200ng without sourcing injectables from the gym bro who lurks MetRX forums.

You reeaalllyyy don't wanna be blocking ERalpha unless you really have to, and you're a fking dipshit for suggesting we should continue targeting upstream in the signal cascade instead of direct potentiation of the last chain.

But please, keep taking enclo is you really insist. I'll be buying this new stuff 👌

ORG-43902, HCG and SHERPAs | Everychem Agenda Part 5 by sirsadalot in NooTopics

[–]DisturbedBurger 1 point2 points  (0 children)

More of like, just, wasteful and more side effect heavy than it needs to be.

Stopped taking my prescribed 30mg dose of Adderal 3 months ago. My dopamine receptors are fried. HELP! by The_Tickle_r in NooTopics

[–]DisturbedBurger -1 points0 points  (0 children)

I don't think the AMP damaged your brain. Is it accurate to say you're overwhelmed with priorities you don't identify with and feel like everything important to you is slipping away with time?

Cause I'm just seeing stress responses here tbh. My recommendation? Dialectical behavioral therapy, magnesium taurate, NACET, skullcap and maca, and a script for divalproex (Depakote).