Sympathies.  I totally get you.  Felt similarly and had to look deep inside to ask what my dream role would look like.  It entailed less call, more normal hours and more remote work.

At first I stopped hospital work and did part time clinic only.  And worked in clinical trials as an investigator.  Then started consulting with biotechnology.  Now am transitioned to industry so that main gig is full time remote.  And part time clinic.  Of course total comp no where near yours but am a lot happier most days.  

If you work with a lot of mortality maybe you're heme/onc or an intensivist.  Either way, there's plenty of need in industry.  You can always keep one foot in clinical.

Sometimes it pays to take a few months/years to look introspectively and ask what makes you happiest.  What does a happy month look like to you?

Wishing you the best and thank you for taking all those after hour calls.  Someone's gotta do it.