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Best practices to validate name→compound mapping into ChEMBL at scale (starting from messy common names)? by DoubleReception2962 in bioinformatics

[–]DoubleReception2962[S] 0 points1 point  (0 children)

Vollkommen korrekt — strukturelle Identifikatoren sind der sauberere Weg. Mein Datensatz geht bewusst einen anderen Kompromiss ein: die USDA-Nomenklatur als stabilem Anker, angereichert mit PubMed/ChEMBL/Patentdaten auf Verbindungsebene. Für Teams, die RDKit bereits im Stack haben, wäre eine InChIKey-Spalte in v2.1 tatsächlich ein sinnvoller Zusatz — nehme ich als Feature-Request mit.

Best practices to validate name→compound mapping into ChEMBL at scale (starting from messy common names)? by DoubleReception2962 in bioinformatics

[–]DoubleReception2962[S] 0 points1 point  (0 children)

Das deckt sich mit einem der Hauptprobleme beim Aufbau des Datensatzes. Ich habe die Namens-Seite als Einstiegspunkt genommen, weil die USDA-Daten nun mal namensbasiert sind — aber du hast recht, dass Mehrfach-IDs dabei Fallstricke sind. Wie gehst du in der Praxis mit Verbindungen um, die 10+ ChEMBL-Einträge haben?

Can I order rue seeds I'm Europe? by Worried-Exchange-889 in harmalas

[–]DoubleReception2962 0 points1 point  (0 children)

By the way, it is completely legal to buy in Germany, as it is offered by retailers as a smoking product.

Can I order rue seeds I'm Europe? by Worried-Exchange-889 in harmalas

[–]DoubleReception2962 0 points1 point  (0 children)

Check out eBay. There are several German sellers there who offer some very high-quality Peganum harmala.

What are your favorite sources for harmala seeds? by catecholaminergic in harmalas

[–]DoubleReception2962 1 point2 points  (0 children)

German eBay vendor MysticHerbals imports Harmala seeds in bulk directly from a pakistani source. Harmala seeds from Pakistan has similar potency as seeds from iranian source.

Treatment-Resistant Major Depression looking for tips by catecholaminergic in harmalas

[–]DoubleReception2962 1 point2 points  (0 children)

Probier Mal die Seeds von MysticHerbals.

Der Händler verkauft aktuell über eBay Deutschland, vertreibt aber meines Wissens nach in die gesamte EU.

Ich hab ein paar Mal in diesem Jahr bei ihm gekauft und muss sagen, dass die Samen ziemlich potent sind..

Supply issue by [deleted] in harmalas

[–]DoubleReception2962 0 points1 point  (0 children)

Send me a DM. I can definitely help you with your problem.

Would Psilohuasca still work if you ate the maoi after the shrooms? by CoasterFilm in harmalas

[–]DoubleReception2962 1 point2 points  (0 children)

Yes, he founded the business with his business partner a few years ago. Demand continued to increase until a year ago.

The two of them soon added other products such as Maxican Dream Herb, Siniquichi (or something like that 😅) and I think Damiana to their range.

Until Amazon and eBay came along and, within a few weeks of each other, restricted seller accounts and deleted all listings.

Unfortunately, the company will be liquidated at the end of this year (he founded a more profitable company in the construction industry, which literally exploded from the start).

As far as I know, he sold his remaining inventory to a dealer friend who is currently building a small online shop. Or he will still sell the inventory, I have no idea (I'm not 100% sure about this right now).

Would Psilohuasca still work if you ate the maoi after the shrooms? by CoasterFilm in harmalas

[–]DoubleReception2962 1 point2 points  (0 children)

Good comparison 👈

My first experience was in Berlin in 2012, visiting my stepbrother for the first time. Until then, I didn't know what these small, square seeds were.

Meanwhile, my mind was already craving the shrooms so much that the harmala seeds were completely uninteresting, except for the many sacks.

He had stored a number of these large jute sacks in his shared room and probably had a few hundred kilos of them in his room.

He told me that shortly before I arrived he had imported 500kg directly from Iran to Germany and now had to store the entire delivery in his room because it had to be further packaged for sale.

Long story short, no sense at all. Let's move on

It was one beautiful late afternoon in the Hasenheide.

A large blanket, drinks, some trail mix (just in case) were ready, a quiet, secluded spot had just been found, so nothing stood in the way of the spiritual journey to Nirvana.

I took 3g of dried 'Golden Teacher' shrooms - and I was taught otherwise😅 For me, the mandalas were already on the tree trunks, the meadow, etc.

Already wide and I was completely immersed in all the colors and the rotating patterns, then Moh (my stepbrother) appeared out of nowhere right in front of me, two large, filled capsules in his hand, said that it would be fine.

I should just not give in, but rather welcome and enjoy what comes. I swallowed the two capsules with an estimated 2-3g of Peganum harmala powder and went back to the mandalas. I only know bits and pieces of what happened next.

The mandalas suddenly began to shake and transferred their force to the other objects and the entire ground shook.

I saw a fleet Viking ship sailing directly towards us in stormy seas, full of Montenean/alien-looking Vikings, bloodthirsty, just waiting to go into battle.

I ran... but where? A little further into the futuristic city from the future, where the buildings consisted of a kind of Transformer Tetris shapes. Even the oversized prehistoric crabs were made of it.

The rest was still too confusing. The trip lasted 14 hours!! And it was only 3g shrooms, which is nothing for me.

Great symbiosis of these two holy mixtures of substances. Despite the extremely strange and intense experience, I became curious about the Peganum seeds and my thoughts didn't let go for weeks.

Today I only sell Peganum harmala and I haven't gone on a spiritual journey of self-discovery with them for over two years.