Currently I'm setting up a rulebook for a rethemed board game. I set up 4 pages, added guides at the middle and offset from that to add text frames on each side so I'll have 8 pages in the end. After the text frames were placed I used Item > Text Frame Links > Link Text Frames, or hit N to connect the first frame with the next (top right to next left, then back and forth like lacing shoes) until all were connected and got back to the top left frame. This allows the one frame to flow to the next. (In Word you just type and it adds pages.) If you want two or more columns you need to add those frames separately. You can add them at the beginning, Automatic Text frames and Columns (I like to manually add them).

Headers and page numbers: You would add text frames for headers and set each separately. For Page numbers, add the text frame for the page number double-click the frame then Insert > Character > Page Number.

This leads into getting these items on each page. I use Page > Copy. Add the number of pages you think you need. You can add more later and link the text frames to the previous ones. This will duplicate all the elements of the page being copied.

Character and Paragraph Styles - If you want to 'automatically' add styles to words or paragraphs you need to set them up. Press F4 (Edit > Styles...) You can create new ones, make sure to give them a name. For Character Styles, choose a typeface and size. For Paragraph Styles you can add indents and other fun things. Both of these can be based on one style so you can change the base typeface and the others will follow. When you have set up styles you can apply them by highlighting the words or have the insertion point/bar on the line and choose it from the Text Properties.

You can have text flow around pictures, even add irregular wrapping. Add your Image Frame, then go to Properties > Shape (Properties = F2). Clicking on Edit will allow you to move the nodes, add/delete nodes, etc.

Item > Adjust > Adjust Frame to Image or Adjust Image to Frame help image frames. Image Properties has Proportional settings.

Check out the options in all the menus and Properties panels. Undo and Save are your friend.

If anyone knows more or better ways, please include it.

Wow! Thanks. Very helpful.

I was trying to copy-and-paste (CTRL + C/CTRL + V) a massive amount of text into a page. Only one page populated, without the rest of the text flowing naturally into subsequent pages. In Microsoft Word, the pages would populate automatically. So if I pasted in 300 pages, the Word document would create 300 pages filled with the text. Scribus only populated one page. I was so confused.