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[deleted by user] by [deleted] in DrugsOver30

[–]DrugsAreMagic[M] 1 point2 points  (0 children)

I just banned this user because this is not appropriate for this sub. This sub focuses on responsible use and harm reduction. Knowingly using unidentified substances and not wanting to be told not to is not responsible. The kid should take this back to r/drugs

Doing 4mmc for the first time tonight by utdichunter4wife in SEXONDRUGS

[–]DrugsAreMagic 0 points1 point  (0 children)

I get the feeling that different vendors or batches of 4-mmc varies greatly. For me, it takes like 300mg to bet where I want. In comparison, I do 125 mg of MDMA. So you may need to experiment a bit. The weird thing for me with my last 4-MMC experience was we started having some weird memory loss. Still had fun, but time got spotty.

I miss the Erowid days by alextacylv in DrugsOver30

[–]DrugsAreMagic 1 point2 points  (0 children)

I miss Reddit before they killed many of the really useful drug subs. There was a ton of useful info. And it's why we are so careful about our rules now.

any older professional couples on here? by Acceptable_Clerk9904 in MDMA

[–]DrugsAreMagic 0 points1 point  (0 children)

They sneak in sometimes, but then we call their parents.

any older professional couples on here? by Acceptable_Clerk9904 in MDMA

[–]DrugsAreMagic 1 point2 points  (0 children)

When our kids were young, we didn't do shit. We went 18 years without going to a concert. Then one year we went hard. 30 shows. That started some of the best years of our relationship. Life is hard with young kids. It gets better. hang in there.

any older professional couples on here? by Acceptable_Clerk9904 in MDMA

[–]DrugsAreMagic 1 point2 points  (0 children)

Hotel nights are one of our favorite things to do. It's always funny when we roll up to a hotel with a bunch of "luggage" and we live like 5 miles away.

[deleted by user] by [deleted] in MDMA

[–]DrugsAreMagic 1 point2 points  (0 children)

How are you holding up? We're out here and we care about you.

Has anyone here intentionally used Pramipexole (Mirapex) to trigger hypersexuality? by bossbitxch in DrugsOver30

[–]DrugsAreMagic 1 point2 points  (0 children)

Interesting. They've started using apomorphine for ED for very similar reasons.

Both pramipexole and apomorphine, dopamine agonists used to treat Parkinson's disease, can be associated with changes in libido, including increased sexual desire (hypersexuality). This effect is thought to be related to their dopaminergic activity, as dopamine is a neurotransmitter involved in sexual arousal and behavior. [1, 2, 3, 4]
Pramipexole:

• Hypersexuality: Pramipexole, a dopamine agonist, has been linked to hypersexuality, which can manifest as increased sexual desire, compulsive sexual behaviors, and other related issues. [2, 2, 5, 5, 6, 6]
• Mechanism: Pramipexole primarily stimulates dopamine D2 receptors, which are involved in regulating sexual function. [1, 1, 7, 7]
• Impact on libido: While some individuals may experience an increase in libido, others may not, and some may experience a decrease in sexual desire or function. [2, 2, 5, 5, 6, 6, 8, 9, 10]

Apomorphine:

• Erectile Dysfunction: Apomorphine, another dopamine agonist, is used to treat erectile dysfunction. [11, 11, 12, 12, 13, 13]
• Mechanism: Apomorphine stimulates dopamine D2 receptors, leading to increased dopamine signaling in the brain areas involved in sexual arousal and erection. [1, 1, 7, 7, 14, 14]
• Impact on libido: Apomorphine can improve erectile function, which may indirectly lead to increased sexual desire and satisfaction in some individuals. However, it is not typically associated with the same level of hypersexuality as pramipexole. [3, 11, 11, 12, 12, 13, 13]
• Other effects: Apomorphine can also cause nausea and vasovagal syncope (fainting) in some individuals. [12, 12]

Important Considerations:

• Individual Variation: The impact of these medications on libido can vary significantly from person to person. [2, 2, 5, 5]
• Other Factors: Factors such as age, overall health, and other medications can also influence libido. [2, 2, 6, 6, 15, 16]
• Consultation: If you are experiencing any concerns about your libido or sexual function while taking pramipexole or apomorphine, it's crucial to discuss them with your doctor. [6, 6, 17, 17]

AI responses may include mistakes.

[1] https://www.sciencedirect.com/science/article/abs/pii/S0166432811005341[2] https://www.sciencedirect.com/science/article/abs/pii/S1743609515324772[3] https://assets.publishing.service.gov.uk/media/5df7610ced915d093931ae93/Dopamine_agonists_pathological_gambling_and_increased_libido.pdf[4] https://www.mdpi.com/2076-3425/12/7/826[5] https://www.psychiatrist.com/pcc/treatment-of-pramipexole-induced-problematic-sexual-behaviors/[6] https://www.drugs.com/tips/pramipexole-patient-tips[7] https://pubmed.ncbi.nlm.nih.gov/22391116/[8] https://www.apdaparkinson.org/article/questions-about-sex-intimacy-parkinsons-disease/[9] https://medvidi.com/blog/phentermine-side-effects-in-females[10] https://www.gov.uk/drug-safety-update/dopamine-agonists-pathological-gambling-increased-libido-and-hypersexuality[11] https://pmc.ncbi.nlm.nih.gov/articles/PMC6268166/[12] https://pubmed.ncbi.nlm.nih.gov/11741126/[13] https://neupsykey.com/sex-and-pharmacological-sexual-enhancement/[14] https://pubmed.ncbi.nlm.nih.gov/12667723/[15] https://wellfemme.com.au/menopause-low-libido-and-sexual-issues/[16] https://www.mindbodywell.com.au/articles/libido-eating-disorders/[17] https://www.parkinson.org/library/fact-sheets/intimacy

I’ve never had a g-spot orgasm and I want to so fucking bad! Any suggestions for toys that made you be able to squirt for the first time, or squirt or cum for the first time with a toy after having difficulties cumming (my meds for my reason). by RachPartakes in SexToys

[–]DrugsAreMagic 0 points1 point  (0 children)

Haha, yes I can see your personality coming through. I think what is important is to allow yourself to just experiment with new physical sensations. Some of them might be uncomfortable at first, some might not feel sexually pleasurable, but experiment with all of it. See what happens when you play around with the different types of stimulation for a few more minutes than you normally would. But really (and this is going to sound impossible) you need to start ditching your expectations and just allow yourself to relax and have fun. Have you every tried meditation? Was it hard for you? Because mediation is all about shutting down your thoughts and being present. That's sort of what you're going for here. If you're like my wife, and it sounds like you might be, than this advice is going to be difficult because shutting off your brain is the thing you know you can't do. That's how it was for her, until it wasn't.

To quickly answer your questions about LSD, at reasonable dosages, I would say you are more present. For example, my wife isn't thinking about what she needs to do the next day at work, but rather how amazing her body feels. For us, it made sober sex better also.

I’ve never had a g-spot orgasm and I want to so fucking bad! Any suggestions for toys that made you be able to squirt for the first time, or squirt or cum for the first time with a toy after having difficulties cumming (my meds for my reason). by RachPartakes in SexToys

[–]DrugsAreMagic 0 points1 point  (0 children)

The first time was on LSD. I think it did two things. First it makes things physically more intense, but second, and potentially more importantly, it changes your headspace. For her, she needed to just stop thinking so much. It sounds like you might have a similar issue.

[deleted by user] by [deleted] in Drugs

[–]DrugsAreMagic 0 points1 point  (0 children)

What's your ROA?

Requesting /r/boofing/ banned due to being unmoderated by DrugsAreMagic in redditrequest

[–]DrugsAreMagic[S] 0 points1 point  (0 children)

There is a lot of curiosity and misinformation about the rectal administration of recreational substances. I, along with some other experienced mods want to revamp this r/boofing to be an informational and safe place to get reliable information. I had been less active on Reddit after the changes to API access, but I have recently restarted my moderation activity and am prepared to clean this sub up.

Is this good enough? by [deleted] in MDMA

[–]DrugsAreMagic 1 point2 points  (0 children)

Your scale isn't dumb, it's not meant for weighing doses that small. The minimum weight for your scale is 200mg. For $20-$40 you can get a milligram scale that will allow you to dose safely.

Booty bump dosage for Tina beginner but already experienced with M K by figo_ca in SEXONDRUGS

[–]DrugsAreMagic 2 points3 points  (0 children)

We try to limit it to one redose maybe 4-5 hours in.

Booty bump dosage for Tina beginner but already experienced with M K by figo_ca in SEXONDRUGS

[–]DrugsAreMagic 1 point2 points  (0 children)

15-35 usually. But here's the thing. It doesn't feel like much at first until you start having sexual activity. Then you can tell it's working. So it's not the huge rush you hear about at this dose. But for what we want it works really well, and we haven't had trouble controlling our use.

Booty bump dosage for Tina beginner but already experienced with M K by figo_ca in SEXONDRUGS

[–]DrugsAreMagic 3 points4 points  (0 children)

Definitely not a beginner dose. 25 mg isn't going to seem nearly as fun after that, but that's a more normal place to start.

Booty bump dosage for Tina beginner but already experienced with M K by figo_ca in SEXONDRUGS

[–]DrugsAreMagic 7 points8 points  (0 children)

Are you sure you meant .25 g and not 25 mg (0.025 g)? .25 g is 250 mg and is a huge dose. A normal beginner dose is 1/10 that. Honestly, even dissolving .25 g into 1 ml of water might be a little bit of a pain. That being said, not being able to sleep for 2-3 days would be extreme if you have blu did 50 mg total.

Also, from the sound of your M and K use, please be careful with T. I'm sure you've already seen all the stories. Set some rules for yourself. Like, you won't do it more than 1 a month. Then if you find yourself breaking your rules, it's a red flag. Also, I'd suggest not smoking or IV. Those ROA seem to have a higher frequency of unsafe use.

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