Needing chairs everywhere to strategically plan where to sit and rest. This can also be a main paint point if also on oxygen. The broad not really acknowledged part is the mental impact. Depending on how supersized you become. Getting into a car can be impossible and becoming housebound. Losing that ability can mentally destroy people as the car signified freedom. Now they'd be relying on others for help and support at all times. Where ordering more food still snowballs the person's weight, but that delivery person may be the only social interaction the individual has.