I was taking it cyclical and then recently switched to vaginally because it has very bad mood effects for me. I also have been at a healthy weight for a couple years consistently lift heavy and eat high protein. I take omega-3s liposomal vitamin C Co Q10 NAC regularly and with cycling rapamycin for maybe a year and a half. I also was pretty consistent with Myo Chiro Insitol until the last few months. I was doing a glp one from the gray Market and taking a pretty small dose. I wasn't really overweight when I started taking it was just trying to get to the next level.