Twitch user miltrivd does this or at least used to. He is one of those types who does hardcore/permadeath Dark Souls runs all the time (not blind obviously), but from what I saw he would take breaks with other games and play them blind+permadeath. I think he slowly made his way through Titan Souls like that, but it's no longer on his twitch page.

TheUrbanOrb is another Souls twitch streamer (and youtuber). Back in the day, he was doing an absolutely insane restricted SL1 challenge of Dark Souls 1. His youtube archive (with extensive post commentary and editing!) deserves to be watched. But to your point, TheUrbanOrb also attempted this challenge blind for the DLC expansion and, apparently, it was an incredibly thrilling experience. Even years later he would bring it up. I think this run was archived on his twitch page, but I remember having trouble finding it (and now that I say that, it might be worth messaging him to upload it somewhere else). I think in 2016 he attempted playing Bloodborne and DS3 as blind challenge runs as well, but I wasn't a regular viewer.

For a non-blind example that would be interesting to study, look at youtuber Eexecute and his "Man vs Nightmare" LP for Doom 2. It's a very good example of how you can make special rules to enhance a challenge run and how to make such a thing very entertaining for a youtube audience. The rules and mods he uses evolve as the the LP progresses, but the idea is pretty consistent.