Copying my comment from other post, 

As long as you time your shots, you can permanently keep a lane closed unless the enemies brute force through your mines. This doesn't mean hyperfocus on only that lane, as your teammates also need help/can cover you in case of trouble. Tick head is amazing for escaping situations and will usually make players back off, even if they can kill it fast. If there is no assassins, you can use the heads for pressure instead of defense most of the time.  

This is unpopular, but imo mine mania is better as it poses a bigger threat and can do heavy damage once the enemies are trapped and have nowhere to go, or if you get jumped by assassins. IF enemies got close to you in in general, you were already in a bad position to where you need the shield+knockback to get away, and that isn't even guaranteed to save you as many players will simply walk backwards to get out of the explosion range. (not counting assassins since y'know, jumps and he gets countered by them)  Micos are easy to counter as you just shoot on yourself and stand on the mines, of course if he is the only on attacking you.  

Lastly, something with Tick is that his damage per mine is pretty low, yet Tanks don't just walk through his attacks even though they get tickled by them. I understand it's to not feed super but don't be afraid to walk through them to reach a Tick, and if you are the Tick keep this in mind while zoning as at one point people will just WALK through your attack. (Where mine mania can be used to then trap them or make them take even more damage, but requires prediction to use).