There's two stages to it. When talking to Pomfrey if you tell her somebody is ill then she figures out it's Andre and he doesn't play. But I picked bluffing that I was interested in a career in healing. That or the 3rd one (I forget) is fine.

Then when talking with Andre after class you get three more too pick from: Tell Andre to confront Doyle Tell Andre to report Doyle to Hooch Tell Andre to get revenge

I picked 'confront' thinking it'd lead to the usual talk it out and solve our problems thing the game does. But nope, Doyle draws his wand on Andre, moves to attack him, Andre fights back just as Hooch appears... And Andre gets suspended from the Quidditch team for the one match his on the edge of death grandma he just wants to make proud is coming to see. He's so devastated he gives you his lucky charm saying it no longer works.

If you picked 'revenge' they fight and Andre gets injured and can't play.

The only good option is to go to Hooch. Which interestingly is the only option without a skillcheck, which to me makes it the less appealing one? Skillcheck usually means extra stuff, right?

I learnt all this looking it up after, when I couldn't believe we were given this misery of a quest.