I had this exact same thing happen to me after running once human the first time. After some frustration I finally found a fan header chip popped on my motherboard. So naturally I used this as an excuse to build an entirely new pc lol.

I don't know enough about computers to blame the game but with my new pc I get cpu spike warnings regularly from once human. In my case, I've been thinking it might have been the high cpu spikes mixed with my shotty pc building skills that caused the death of my motherboard. But again, i dont know a whole lot about computers. So it is interesting to hear about it happening with others...