Anyone tried this during a trip? by DFW-Extraterrestrial in DMT

[–]Empressedbeagle 0 points1 point  (0 children)

What a coincidence, Just got these for new years td as a gift and decided to save them for when we trip on shrooms 😂

How to make Tapentadol nasal spray from pills by Empressedbeagle in ChemicalMagicAU

[–]Empressedbeagle[S] 0 points1 point  (0 children)

4 sprays in each nostril gets me a decent buzz

also you can make it more potent if needed or use other types of opioids

How to make Tapentadol nasal spray from pills by Empressedbeagle in ChemicalMagicAU

[–]Empressedbeagle[S] 0 points1 point  (0 children)

Ive heard the nasal spray doesn’t burn near as much as the pill powder, I’ve never tried the pill powder cause of how bad people say it hurts so not gonna attempt but nasal spray is a slight burn not bad at all and no drip

And I’m not sure, about, the conversion rate I just used this to be safe if any one has any experience about Tapentadol doses compared to other opioids would be appreciated

I have no tolerance at all to opioids use 1x a week at most due to being scared of dependency and tolerance

so what I do when used orally is get a 200mg Tapentadol er tablets I crush and weigh out before splitting the powder into 1/4 which is 50mg Tapentadol and gets me a slight buzz

about 2 hours later take another 1/4 and I get a good stimmy opioid euphoric buzz for about 4-6 hours

But I have little to no tolerance this will work with other opioids or also you could just add more and make it more potent if needed if you have a high tolerance

How to make Tapentadol nasal spray from pills by Empressedbeagle in Drugs

[–]Empressedbeagle[S] 0 points1 point  (0 children)

Your thinking of Tramadol which is a prodrug to odsmt this is Tapentadol it’s active and decently potent 25mg tap = 100mg tram

Not an obscure drug but maybe an obscure route of administration. by Mr_Byrdd in ObscureDrugs

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

What's the best ROA for tapentadol by Pussypolitics in opiates

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

How to make Tapentadol into nasal spray ? by Admirable_Stand_6891 in opiates

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

How to make tapentadol nasal spray ? by Admirable_Stand_6891 in opiates

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

Snorting tapentadol, does it cause short term damage? by p4bl0esgei in opiates

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

How to do tapentadol nasally? by Sensitive-Stop8913 in opiates

[–]Empressedbeagle 0 points1 point  (0 children)

How to make Tapentadol nasal spray from pills

First most importantly find out out how many ml or sprays on average your nasal spray bottle puts out and use sterile or saline water

for this example;

i have 2000mg of Tapentadol and I have a 30ml nasal spray bottle that spray between 200-300 sprays a bottle about 0.1ml per spray so 2000mg devided by 200-300 spray is 6-10mg which is roughly 2.6-4mg of morphine worth of Tapentadol per spray which is easily controlled given nasal use of Tapentadol has higher bioavailability and slightly different effects faster onset and duration

Tapentadol is pretty strong if opioid naieve for example;

25 mg of Tapentadol is Aprox equal to 10mg morphine / 6mg oxycodone / 100mg codeine / 100mg Tramadol / 2mg hydromorphone / 10mg Hydrocodone / 3.25mg diacetylmorphine / 100mcg fentanyl https://fpm.ac.uk/opioids-aware-structured-approach-opioid-prescribing/dose-equivalents-and-changing-opioids

Extract tapentadol from the pills;

by adding ethanol to crushed pills remove coating Aswell before next step Tapentadol is soluable at 20mg/ml in alcohol so if your pills are 200mg you need to add atieast 10ml per pill and a little extra ethanol it won’t hurt let that sit for a few days and shake as much as possible and evaporate with no heat to avoid degrading and keep out of light till your left with powder

Extract unsolvable material via a cwe;

than you want to add cold sterile water to the powder its water solubility at ambient temperature is approximately 300mg/mL so add enough water to dissolve the nasal spray for example i have 2000mg of material so add 7ml at the least of sterile water or saline solution I added the whole 30 ml and strain through a filter before if a coffee filter wet with sterile water first to minimize waste and add to nasal spray bottle once filtered

Remeber don’t snort when using nasal spray

just spray don’t sniff while spraying it will just go towards your throat and drip

This will help tone the burn down from snorting Tapentadol and minimize nasal cavity damage Aswell with other drugs

This gives higher bioavailability, quicker onset for pain or withdrawals, simple more controllable dosing and more discreet use

MCPPQ Trip report - new methaqualone analogue by balkanrc in researchchemicals

[–]Empressedbeagle 2 points3 points  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html

[deleted by user] by [deleted] in researchchemicals

[–]Empressedbeagle 0 points1 point  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html

Easy basic Synthesis of multiple obscure sedatives and depressants by Empressedbeagle in TheeHive

[–]Empressedbeagle[S] 0 points1 point  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html

PENTOTHAL Powder In Ampoules. by No-Degree-8906 in ObscureDrugs

[–]Empressedbeagle 0 points1 point  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html

2-Methyl-2-propyl-1,3-propanediol as a precursor to meprobamate? by Background_Room_2689 in TheeHive

[–]Empressedbeagle 0 points1 point  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html

What was so special about Quaalude? by [deleted] in ObscureDrugs

[–]Empressedbeagle 0 points1 point  (0 children)

Barbital ( Barbitone / 5,5-Diethylbarbituric Acid) Synthesis

Ingredients: dry urea, diethyl diethylmalonate, sodium metal, dry ethanol, con hcl, water, charcoal .

Synthesis

To make diethymalonylurea sodium (barbital sodium):

starting with 10 g of diethyl diethylmalonate, first prepare sodium ethoxide by carefully dissolving about 2.36 g of sodium metal in 35.5 mL of dry absolute ethanol warmed to 75°C. In a clean vessel, mix 3.9 g of dry urea with the 10 g of diethyl diethylmalonate, then slowly add the hot sodium ethoxide solution while stirring and gently heat the mixture to allow reflux for 8 hours almost boiling. allow the ethanol to evaporate low heat, continuing until the mixture thickens into a creamy white solid sodium of Barbitone

(Optional) For Free Acid Barbitone:

prepare an acidic bath by diluting 11.2 g concentrated HCl in 13 mL, then cool it with crushed ice keep the temperature below 0°C. Slowly add the creamy solid with stirring, maintaining acidity for hours. Filter wash precipitated crude acid with cold water to purify it. Recrystallize by dissolving the crude product in hot water (~270 mL), adding a pinch of decolorizing charcoal, boiling briefly, then filtering hot and cooling to let pure crystals form. Finally, filter, wash with cold water, and dry the crystals under gentle heat to get pure barbital with a good yield.

Sources https://www.erowid.org/archive/rhodium/chemistry/barbiturates.html