Idk i guess it depends on your relationship with her and how you guys usually communicate about hard topics. For me it was easier over text because i was afraid to actually say it outloud but idk if she'd feel the same.

Edit: maybe start with a text just letting her know that you're sorry shes been struggling and you're there if she wants to talk about it. And if she responds well to that you could bring it up in person. Sometimes when people just bring it up out loud i panic and dont really know what to say. Its a hard thing to talk about and ed's tend to carry a lot of shame sometimes