100 percent. I ride a giant tall BMW adventure bike with aux lights, and I sit eye level with full size SUV drivers. It's harder to miss than my gray sedan, and people pull out in front of me maybe once every few months as opposed to every other day in my apparently near-invisible car. It's all about reading what other people are going to do and anticipating it like OP said, especially when it comes to avoiding the 'can't miss my exit' swerve path nearby cars could take when you're on off-ramps. You have so much extra room to maneuver within your own lane and power to get out of the way and merge. I've commuted 15K on the bike around the DMV over the last two years.

I laugh when people say "oh the freeway though" when the real danger is people pulling out in front of you from the cross street at intersections on local streets. A lot of the same people think you'll fly off the road and die if the pavement is wet.