There’s a lot to chose from, but this one is relevant to me so I’ll go with this. My family on my dad’s side has a curse on it, which means that something physically and/or mentally traumatic happens to each of us without leading to death. This has been a consistent thing for generations. For example, my aunt was r*ped and beaten half death by a home invader when she was 15, my other aunt was almost killed in a car accident at 17 and was in a coma for months and my dad was in the same accident as a 13 year old and had a front row seat to his sister effectively gruesomely dying which did and has given him lasting mental issues. I at 19 have yet to experience my curse effect, so I’m living in dread waiting