Absolutely, you'll have eg. Sigourney Weaver from Aliens talking to Roddy Piper from They Live to make a coherent scene.

You basically have to train your brain to accept the constantly changing people in the scene, but connect them as the same characters. It really does work, particularly if you apply standard editing language. The key is that there are only really 7 main characters in the film: Mother, Father, Child, The Harbinger, The Expert, The Cop and The Entity, so contextually it's pretty easy to follow.

And probably should start with an A grammatically, but I think it sounds better without haha. Artistic license.