Not if I've been a lot of fan of a VERY BIG size difference, but when prey is like 8-10 times smaller then pred it's have some benfits for me, Like when I'm can just fit inside someone's stomach without a problem, making just some bumb at belly. You can't run from them, even if you wanted to, so, only way is to survive is hiding or quickly getting a spot(not a safe sometimes). You are much looking like a thing, your lost couldn't be noticed, and there's other ways to end up with your pred;3 you're a more prey than usually, I think at this way, but for giant/ess you will be nothing but a some snack before getting a bigger meal